missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

ZO-1 Rat, Clone: R26.4C, eBioscience™

Rat Monoclonal Antibody

$133.32 - $315.48

Specifications

Antigen ZO-1
Clone R26.4C
Host Species Rat
Gene Alias Tight Junction Protein 1
Species Reactivity Canine, Mouse, Rat
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122861 Life Technologies
LS14977680
25μg Each for $133.32
501122862 Life Technologies
LS14977682
100μg Each for $315.48
Specifications

Description

The monoclonal antibody R26.4C recognizes the tight junction protein 1, ZO-1 (zona occludens) of rat, mouse, canine, and porcine. ZO-1 is a member of the MAGUK family of tight junction associated scaffolding proteins, each containing a PDZ, SH3 and guanylate kinase-like (GUK) domain. ZO-1 is an integral member of the tight junction complex which forms a barrier to paracellular movement of substances, separating apical and basolateral fluids in relation to the epithelial cell layer. ZO-1 forms complexes with family members ZO-2, ZO-3, as well as occludin, cingulin, claudin-1-8, actin, alpha-catenin, the Ras-effector molecule AF-6, ZONAB, Apg-2, and the junctional adhesion molecules (JAM)-A-C. ZO-1 is thought to anchor the actin cytoskeleton to the tight junction. ZO-1 and ZO-2 have been shown to regulate cell cycle and proliferation with recent evidence highlighting the down-regulation of ZO-1 and ZO-2 with cancer progression.
Description & Specifications

Specifications

ZO-1
Rat
Canine, Mouse, Rat
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
R26.4C
Tight Junction Protein 1
Immunocytochemistry,Immunohistochemistry (Frozen),Microscopy,Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL