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Tocris™ ZM 336372


Potent, selective c-Raf inhibitor

Manufacturer: tocris™  1321/50

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 Disclaimers

For Research Use Only

Catalog No. 132150

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Description & Specifications

Specifications

Product Type ZM 336372
Inhibitors ZM 336372
Purity >99
Molecular Weight 389.45
Quantity 50mg

Potent, selective inhibitor of c-Raf in vitro (IC50 = 70nM for inhibition of human c-Raf). Shows 10-fold selectivity over B-Raf. Also inhibits SAPK2/p38 (IC50 = 2μM). Selective over 17 other protein kinases including PKA, PKC, p42 MAPK, CDK1 and SAPK1/JNK (up to 50μM). Also available as part of the MAPK Cascade Inhibitor Tocriset™.

  • Chemical Name: 3-(Dimethylamino)-N-[3-[(4-hydroxybenzoyl)-amino]-4-methylphenyl]benzamide
  • Formula: C23H23N3O3
  • CAS Number: 208260-29-1
  • Solubility: Soluble to 100mM in DMSO
  • Purity: >99