Thermo Scientific Chemicals Zeocin^t, 100 mg/ml in HEPES, sterile-filtered

Description

Zeocin, a popular and effective antibiotic for the selection of vectors bearing the Sh ble gene in a variety of cells types (bacteria, eukaryotic microorganisms, plant and animal cells). Resistance to Zeocin is conferred by the Sh ble gene product, which inactivates Zeocin™ by binding to the antibiotic. Sh ble is a small gene, only 370bp in size, carried in a number of InvivoGen’s vectors. Zeocin is used as a selective agent in molecular genetics experiments.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Zeocin (phleomycin) is a glycopeptide from the bleomycin family of antibiotics
• Zeocin intercalates DNA, producing double-stranded breaks and preventing cell division
• It can chelate some active metals including cobalt, iron, and copper
• Zeocin has antineoplastic and antifungal properties

Application

• Zeocin is useful for genetic selection experiments