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Thermo Scientific™ Lab Vision™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-3, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-3, Mouse Monoclonal Antibody. 

Manufacturer: thermo scientific™ lab vision™  MS1393PABX

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Catalog No. MS1393PABX

  • / Each
 

Description & Specifications

Specifications

Format Concentrated
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Cross Reactivity Human
Isotype IgG2a kappa
Immunogen Recombinant human XRCC1 protein
Regulatory Status RUO
Clone 144
Quantity 200µL
Antigen XRCC1 (X-Ray Repair Cross Complementing Protein1) Ab-3
Host Species Mouse
Formulation Ab without BSA/Azide (Frozen)
Concentration 1mg/mL
Purification Method Ls174T, or HeLa cells, normal testis
Research Discipline DNA Repair
Conjugate Unlabeled
Classification Monoclonal
Type Primary

Provide accurate, reproducible results with the Thermo Scientific™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-3, Mouse Monoclonal Antibody. 

X-Ray Repair Cross Complementing (XRCC1) plays a role in excision repair of DNA after ionizing irradiation. XRCC1 binds to DNA ligase III through the C-terminal 96 amino acids and to DNA polymerase β through the N-terminal half. In testis XRCC1 is expressed at high levels. Cells with a mutation of this gene exhibit decreased single strand break repair and reduced recombination repair. They show increased double strand breaks, and sister chromatid exchange is increased up to 10-fold. The XRCC1 might serve as a scaffold protein during base excision-repair.

Host Species: Mouse

Clone: 144

Isotype: IgG2a/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human XRCC1 protein

Molecular Weight: 85kDa

Positive Control: Ls174T, or HeLa cells; normal testis

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO