Thermo Scientific™ Lab Vision™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-3, Mouse Monoclonal Antibody
Provide accurate, reproducible results with the Thermo Scientific™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-3, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS1393PABX
Provide accurate, reproducible results with the Thermo Scientific™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-3, Mouse Monoclonal Antibody.X-Ray Repair Cross Complementing (XRCC1) plays a role in excision repair of DNA after ionizing irradiation. XRCC1 binds to DNA ligase III through the C-terminal 96 amino acids and to DNA polymerase β through the N-terminal half. In testis XRCC1 is expressed at high levels. Cells with a mutation of this gene exhibit decreased single strand break repair and reduced recombination repair. They show increased double strand breaks, and sister chromatid exchange is increased up to 10-fold. The XRCC1 might serve as a scaffold protein during base excision-repair.
Host Species: Mouse
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Recombinant human XRCC1 protein
Molecular Weight: 85kDa
Positive Control: Ls174T, or HeLa cells; normal testis
Cellular Localization: Nuclear
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Denatured verified)
USA: RUO; Int'l: RUO
|XRCC1 (X-Ray Repair Cross Complementing Protein1) Ab-3|
|Ab without BSA/Azide (Frozen)|
|Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting|
|Recombinant human XRCC1 protein|
|Ls174T, or HeLa cells, normal testis|