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XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-1 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-1, Mouse Monoclonal Antibody.
Supplier: Thermo Fisher Scientific MS434P1
Description
X-Ray Repair Cross Complementing (XRCC1) plays a role in excision repair of DNA after ionizing irradiation. XRCC1 binds to DNA ligase III through the C-terminal 96 amino acids and to DNA polymerase β through the N-terminal half. In testis XRCC1 is expressed at high levels. Cells with a mutation of this gene exhibit decreased single strand break repair and reduced recombination repair. They show increased double strand breaks, and sister chromatid exchange is increased up to 10-fold. The XRCC1 might serve as a scaffold protein during base excision-repair.Host Species: Mouse
Clone: 33-2-5
Isotype: IgG2b
Species Reactivity: Human and Rat. Others not known.
Epitope: Not determined
Immunogen: Recombinant human XRCC1 protein
Molecular Weight: 85kDa
Positive Control: Ls174T, HT29 or HeLa cells; normal testis
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Native verified)
Note:
USA: RUO; Int'l: RUO
Specifications
| XRCC1 (X-Ray Repair Cross Complementing Protein1) Ab-1 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 500 μL | |
| DNA Repair | |
| Human, Rat | |
| IgG2b |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 33-2-5 | |
| Unconjugated | |
| Recombinant human XRCC1 protein | |
| RUO | |
| Primary | |
| Concentrated |