Thermo Scientific™ Lab Vision™ XPF Ab-5, Mouse Monoclonal Antibody
Provide accurate, reproducible results with the Thermo Scientific™ XPF Ab-5, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS1385P1ABX
Provide accurate, reproducible results with the Thermo Scientific™ XPF Ab-5, Mouse Monoclonal Antibody.The structure-specific ERCC1/XPF endonuclease complex is implicated in the repair of two distinct types of lesions in DNA: NER for UV-induced lesions and bulky chemical adducts; and recombination repair of the very genotoxic interstrand cross-links. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1-XPF complex makes the 5' incision.
Host Species: Mouse
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Recombinant human XPF protein
Molecular Weight: ∽110kDa
Positive Control: MCF-7 cells
Cellular Localization: Nuclear
- Immunohistochemistry (Not suitable)
- Western Blotting
USA: RUO; Int'l: RUO
|Recombinant human XPF protein|