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Thermo Scientific™ Lab Vision™ XPF Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ XPF Ab-1, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS1381PABX

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Catalog No. MS1381PABX


 

Specifications

Description

Provide accurate, reproducible results with the Thermo Scientific™ XPF Ab-1, Mouse Monoclonal Antibody.

The structure-specific ERCC1/XPF endonuclease complex is implicated in the repair of two distinct types of lesions in DNA: NER for UV-induced lesions and bulky chemical adducts; and recombination repair of the very genotoxic interstrand cross-links. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1-XPF complex makes the 5' incision.

Host Species: Mouse

Clone: 219

Isotype: IgG2/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human XPF protein

Molecular Weight: ∽110kDa

Positive Control: MCF-7 cells or human tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

XPF Ab-1
Monoclonal
1mg/mL
Human
Ab without BSA/Azide (Frozen)
Recombinant human XPF protein
200μL
DNA Repair
Monoclonal
Immunohistochemistry (Paraffin),Western Blotting
219
Unlabeled
Concentrated
Murine
IgG2
RUO
Primary
Human