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Thermo Scientific™ Lab Vision™ XPF Ab-1, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ XPF Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS1381P1ABX

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Catalog No. MS1381P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen XPF Ab-1
Applications Immunohistochemistry (Paraffin)
Applications Western Blotting
Classification Monoclonal
Clone 219
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Mouse
Immunogen Recombinant human XPF protein
Isotype IgG2
Quantity 100µL
Regulatory Status RUO
Research Discipline DNA Repair
Type Primary

Provide accurate, reproducible results with the Thermo Scientific™ XPF Ab-1, Mouse Monoclonal Antibody.

The structure-specific ERCC1/XPF endonuclease complex is implicated in the repair of two distinct types of lesions in DNA: NER for UV-induced lesions and bulky chemical adducts; and recombination repair of the very genotoxic interstrand cross-links. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1-XPF complex makes the 5' incision.

Host Species: Mouse

Clone: 219

Isotype: IgG2/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human XPF protein

Molecular Weight: ∽110kDa

Positive Control: MCF-7 cells or human tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO