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Thermo Scientific™ Lab Vision™ XPA Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ XPA Ab-1, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS650P1ABX

 View more versions of this product

Catalog No. MS650P1ABX


 

Specifications

Description

Provide accurate, reproducible results with the Thermo Scientific™ XPA Ab-1, Mouse Monoclonal Antibody.

The XPA (xeroderma pigmentosum group A) protein specifically recognizes the UV-or chemically damaged DNA lesions, and triggers the nucleotide excision repair process. XPA binds to the replication protein A (RPA) or the excision repair cross complementing 1 protein (ERCC1). In the absence of nucleotide excision repair persisting (unrepaired) DNA lesions (adducts) may lead to the accumulation of gene mutations and ultimately to cancer. Xeroderma pigmentosum patients have a > 2000 fold increased risk to develop skin cancer at sun-exposed areas.

Host Species: Mouse

Clone: 12F5

Isotype: IgG2a/k

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human XPA protein

Molecular Weight: ∽40kDa

Positive Control: Ls174T or MCF-7 cells or human tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

XPA Ab-1
Monoclonal
1mg/mL
Human
Ab without BSA/Azide (Frozen)
Recombinant human XPA protein
100μL
DNA Repair
Monoclonal
Western Blot
12F5
Unlabeled
Concentrated
Murine
IgG2a kappa
RUO
Primary
Human