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Thermo Scientific™ Lab Vision™ von Hippel-Lindau (vHL) Protein Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ von Hippel-Lindau (vHL) Protein Ab-1, Mouse Monoclonal Antibody.

$257.39 - $1,504.43

Specifications

Antigen von Hippel-Lindau (vHL) Protein Ab-1
Clone Ig33
Classification Monoclonal
Cross Reactivity Human
Cross Reactivity Mouse
View More Specs
Products
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity    

MS690B

 
thermo scientific™ lab vision™
MS-690-B
200�g/mL Biotin 1mL Each for $1,504.43

MS690B0

 
thermo scientific™ lab vision™
MS-690-B0
200�g/mL Biotin 100µL Each for $344.63

MS690B1

 
thermo scientific™ lab vision™
MS-690-B1
200�g/mL Biotin 500µL Each for $938.55

MS690P

 
thermo scientific™ lab vision™
MS-690-P
200�g/mL Unlabeled 1mL Each for $1,211.57

MS690P0

 
thermo scientific™ lab vision™
MS-690-P0
200�g/mL Unlabeled 100µL Each for $257.39

MS690P1

 
thermo scientific™ lab vision™
MS-690-P1
200�g/mL Unlabeled 500µL Each for $724.45

MS690P1ABX

 
thermo scientific™ lab vision™
MS690P1ABX
1mg/mL Unlabeled 100µL Each for $788.29

MS690PABX

 
thermo scientific™ lab vision™
MS-690-PABX
1mg/mL Unlabeled 200µL Each for $1,298.86
Description & Specifications

Specifications

Antigen von Hippel-Lindau (vHL) Protein Ab-1
Clone Ig33
Classification Monoclonal
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Human
Cross Reactivity Mouse
Format Concentrated
Host Species Mouse
Regulatory Status RUO
Research Discipline Cancer and Tumor Biology
Type Primary
Immunogen A recombinant protein containing aa 1-213 of human VHL
Isotype IgG2a kappa

Provide accurate, reproducible results with the Thermo Scientific™ von Hippel-Lindau (vHL) Protein Ab-1, Mouse Monoclonal Antibody.

Molecular genetic studies suggest that VHL is a tumor-suppressor gene. Alterations in the von Hippel-Lindau (VHL) gene are correlated with a diverse group of neoplasms including hemangioblastoma, clear cell renal carcinoma (RCC), and pheochromocytoma. Two transcriptional elongation factors, Elongin B and C, are shown to bind in vitro and in vivo to a short, colinear region of the VHL protein (pVHL) that is frequently mutated in human tumors. It is proposed that pVHL functions in vivo as a negative regulator of transcription elongation.

Host Species: Mouse

Clone: Ig33

Isotype: IgG1/κ

Species Reactivity: Human and Mouse. Others not known.

Epitope: aa 1-54

Immunogen: A recombinant protein containing aa 1-213 of human vHL

Molecular Weight: 30kDa

Positive Control: Kidney

Cellular Localization: Cytoplasmic Ab-1 does not recognize the truncated form of VHL protein.

Note:

USA: RUO; Int'l: RUO