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Thermo Scientific™ Lab Vision™ Vitamin D Receptor (VDR) Ab-1, Rat Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ Vitamin D Receptor (VDR) Ab-1, Rat Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  RT200P1ABX

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Catalog No. RT200P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen Vitamin D Receptor (VDR) Ab-1
Applications Western Blotting
Classification Monoclonal
Clone 9A7gamma.E10.E4
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Chicken
Cross Reactivity Fish
Cross Reactivity Frog
Cross Reactivity Hamster
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Porcine
Format Concentrated
Host Species Rat
Immunogen Vitamin D receptor protein from chicken intestine
Isotype IgG2b
Quantity 100µL
Regulatory Status RUO
Research Discipline Nuclear Receptors
Type Primary

Provide accurate, reproducible results with the Thermo Scientific™ Vitamin D Receptor (VDR) Ab-1, Rat Monoclonal Antibody.

VDR is a member of super family of steroid hormone receptors. It is known to play role in cellular growth and differentiation, calcium and phosphorus metabolism and bone remodeling. Human breast carcinomas, leukemias, and prostatic carcinoma cells express VDR, which can modify their growth and differentiation. In avians, VDR appears as a doublet of 58kDa and 60kDa.

Host Species: Rat

Clone: 9A7γ.E10.E4

Isotype: IgG2b

Species Reactivity: Human, Pig, Mouse, Rat, Hamster, Frog, Chicken and Fish. Others not known.

Epitope: aa 89-105 (near the DNA-binding domain)

Immunogen: Vitamin D receptor protein from chicken intestine

Molecular Weight: 53kDa

Positive Control: LNCAP cells, HeLa cells

Cellular Localization: Nuclear Ab-1 reacts with both the occupied and unoccupied forms of VDR and shows no cross reaction with estrogen and glucocorticoid receptors. It is excellent for biochemical and histochemical applications.

Recommended for:

  • Western Blotting
  • Gel Supershift Assay

Note:

USA: RUO; Int'l: RUO