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V beta 11 TCR Rat anti-Mouse, APC, Clone: RR3-15, eBioscience™

Rat Monoclonal Antibody

$157.08 - $394.68

Specifications

Antigen V beta 11 TCR
Clone RR3-15
Host Species Rat
Gene Alias Vb11, Vbeta11
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123143 Life Technologies
LS17582780
25μg Each for $157.08
501123144 Life Technologies
LS17582782
100μg Each for $394.68
Specifications

Description

This RR3-15 monoclonal antibody reacts with the mouse T-cell receptor (TCR) V beta 11 chain. Composed of an alpha and beta chain, TCR specificity is typically determined by Va, Ja, Vb, Db, and Jb gene rearrangement. The RR3-15 antibody recognizes the V beta 11 chain on T cells from mouse strains with the b haplotype in the Tcrb gene complex, including C57BL/6 and B10, but is absent in mice with the a haplotype, such as C57L, SJL, and SWR. In addition, reports indicate that Vbeta11+ T cells are eliminated in mice bearing the MHC Class II I-E molecule. Finally, V beta 11+CD4+ T cells have been associated with graft-versus-host disease (GVHD) severity.

The RR3-15 antibody has been reported to activate V beta 11+ T cells.
Description & Specifications

Specifications

V beta 11 TCR
Rat
Flow Cytometry
Allophycocyanin
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL
RR3-15
Vb11, Vbeta11
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer