Please login to your online account to display your discounted pricing

V beta 11 TCR Rat anti-Mouse, APC, Clone: RR3-15, eBioscience™

Rat Monoclonal Antibody

$172.55 - $433.55

Specifications

Antigen V beta 11 TCR
Clone RR3-15
Host Species Rat
Gene Alias Vb11, Vbeta11
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123143

 
affymetrix
17582780
25μg Each for $172.55

501123144

 
affymetrix
17582782
100μg Each for $433.55
Description & Specifications

Specifications

Antigen V beta 11 TCR
Clone RR3-15
Host Species Rat
Gene Alias Vb11, Vbeta11
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

This RR3-15 monoclonal antibody reacts with the mouse T-cell receptor (TCR) V beta 11 chain. Composed of an alpha and beta chain, TCR specificity is typically determined by Va, Ja, Vb, Db, and Jb gene rearrangement. The RR3-15 antibody recognizes the V beta 11 chain on T cells from mouse strains with the b haplotype in the Tcrb gene complex, including C57BL/6 and B10, but is absent in mice with the a haplotype, such as C57L, SJL, and SWR. In addition, reports indicate that Vbeta11+ T cells are eliminated in mice bearing the MHC Class II I-E molecule. Finally, V beta 11+CD4+ T cells have been associated with graft-versus-host disease (GVHD) severity.

The RR3-15 antibody has been reported to activate V beta 11+ T cells.