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Alfa Aesar™ Tyrphostin A23, 99%

Potent inhibitor of EGF receptor kinase activity

$195.49 - $463.32

Chemical Identifiers

CAS 118409-57-7
Molecular Formula C10H6N2O2
Formula Weight 186.17
MDL Number MFCD00133899
Synonym Tyrphostin AG-18; 2-(3,4-Dihydroxybenzylidene)malononitrile
Chemical Name or Material Tyrphostin A23
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Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ60308LB0 SDS Alfa Aesar™
J60308LB0
5mg N/A N/A  
Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
AAJ60308MA SDS Alfa Aesar™
J60308MA
10mg Each for $195.49
AAJ60308MB SDS Alfa Aesar™
J60308MB
25mg Each for $463.32
Specifications

Description

Applications
Tyrphostin inhibit protein tyrosine kinase and block the EGF-dependent autophosphorylation of the receptor. The inhibitors can bind to the EGF receptor kinase domain with different affinities. It also inhibits PDGFR kinase. Tyrphostin A23 has been used to inhibit agonist-induced GP IIb- IIIa activation in permeabilized platelets and in other studies to block calcium channel currents in vascular smooth muscle cells. . Tyrphostin A23 can also inhibit the internalization of (125)I-transferrin in Heb7a cells.

Solubility
Soluble in DMSO, ethanol, or DMF

Notes
Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, acids, heat.
Description & Specifications

Chemical Identifiers

118409-57-7
186.17
Tyrphostin AG-18; 2-(3,4-Dihydroxybenzylidene)malononitrile
C10H6N2O2
MFCD00133899
Tyrphostin A23

Specifications

118409-57-7
C10H6N2O2
MFCD00133899
Soluble in DMSO, ethanol, or DMF
5mg
99%
Powder
186.17
Tyrphostin AG-18; 2-(3,4-Dihydroxybenzylidene)malononitrile
Yellow to Pale Brown
Tyrphostin A23

Safety and Handling

Recommended Storage : −30° to −10°C