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TYK2 Recombinant Human Protein DFS Item

TYK2 Recombinant Human Protein

Manufacturer:  Life Technologies LSPV4790

Catalog No. PV4790



Description

Description

Tyrosine Kinase 2 (TYK2) a member of the JAK kinase family, plays both structural and catalytic roles in type I interferon (IFN) signaling.
Specifications

Specifications

NP_003322.2
Pharma and biopharma, protein assays and analysis, target and lead identification and validation
68.8kDa
80% by SDS-PAGE
–80°C
1 Each
TYK2
TYK2 was pre-diluted in enzyme dilution buffer and assayed in 25mM Tris (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β−glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 100μM ATP, 333μg/mL IRS-1 (Y608) peptide substrate (KKHTDDGYMPMSPGVA) and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinases and inhibitors
JAK kinase family
TYK2 Recombinant Human Protein
Human
0.40mg/mL
7297
TYK2 Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Cytoplasmic tyrosine kinases
TYK2 Recombinant Human Protein
Kinase assay
Baculovirus
aa 833 to 1187
220nmoles of phosphate transferred to IRS-1 (Y608) peptide substrate (KKHTDDGYMPMSPGVA) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 4.17μg/mL
GST Tag
Documents

For Research Use Only. Not for use in diagnostic procedures.