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Thermo Scientific™ Lab Vision™ Tubulin-α Ab-2, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Tubulin-α Ab-2, Mouse Monoclonal Antibody. 

Manufacturer: thermo scientific™ lab vision™  MS581P1ABX

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Catalog No. MS581P1ABX

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Description & Specifications


Antigen Tubulin, alpha Ab-2
Applications Electron Microscopy
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone DM1A
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Chicken
Cross Reactivity Frog
Cross Reactivity Gerbil
Cross Reactivity Guinea Pig
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Porcine
Cross Reactivity Rat
Format Concentrated
Formulation Purified Ab without BSA and Azide
Host Species Murine
Immunogen Native chick brain microtubules
Isotype IgG2a kappa
Quantity 100μL
Regulatory Status RUO
Research Discipline Cytoskeletal Protein
Type Primary
Monoclonal or Polyclonal Monoclonal
Target Species Bovine
Target Species Chicken
Target Species Frog
Target Species Gerbil
Target Species Guinea Pig
Target Species Human
Target Species Murine
Target Species Porcine
Target Species Rat

Provide accurate, reproducible results with the Thermo Scientific™ Tubulin-α Ab-2, Mouse Monoclonal Antibody. 

Microtubules, the major cytoskeletal elements found in all eukaryotic cells, consist of Tubulin, which is a dimer of two 55kDa subunits: α and Β. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton.

Host Species: Mouse

Clone: DM1A

Isotype: IgG1/κ

Species Reactivity: Human, Cow, Pig, Rat, Mouse, Guinea Pig, Gerbil, Frog and Chicken. Others not known.

Epitope: aa 426-450

Immunogen: Native chick brain microtubules

Molecular Weight: 57kDa

Positive Control: Ls174T, MAD109 cells; skin or lung

Cellular Localization: Cytoplasmic Ab-2 causes the 10nm filaments to collapse into large lateral aggregates collecting in the cell periphery or tight juxtanuclear caps. It does not block microtubule assembly. It does not inhibit polymerization or depolymerization of platelet tubulin in vitro. It blocks (by 70-80%) the ability of tubulin dimers (with GppNHp bound) to promote a stable inhibition of adenylyl cyclase.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Electron Microscopy


USA: RUO; Int'l: RUO