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Thermo Scientific™ Lab Vision™ Tubulin-α Ab-2, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Tubulin-α Ab-2, Mouse Monoclonal Antibody. 

Manufacturer: thermo scientific™ lab vision™  MS581P1ABX

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Catalog No. MS581P1ABX

  • / Each

Description & Specifications


Cross Reactivity Bovine
Cross Reactivity Chicken
Cross Reactivity Frog
Cross Reactivity Gerbil
Cross Reactivity Guinea Pig
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Porcine
Cross Reactivity Rat
Clone DM1A
Applications Electron Microscopy
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Host Species Mouse
Format Concentrated
Regulatory Status RUO
Antigen Tubulin, alpha Ab-2
Immunogen Native chick brain microtubules
Quantity 100µL
Isotype IgG2a kappa
Concentration 1mg/mL
Classification Monoclonal
Formulation Purified Ab without BSA and Azide
Conjugate Unlabeled
Research Discipline Cytoskeletal Protein
Type Primary

Provide accurate, reproducible results with the Thermo Scientific™ Tubulin-α Ab-2, Mouse Monoclonal Antibody. 

Microtubules, the major cytoskeletal elements found in all eukaryotic cells, consist of Tubulin, which is a dimer of two 55kDa subunits: α and Β. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton.

Host Species: Mouse

Clone: DM1A

Isotype: IgG1/κ

Species Reactivity: Human, Cow, Pig, Rat, Mouse, Guinea Pig, Gerbil, Frog and Chicken. Others not known.

Epitope: aa 426-450

Immunogen: Native chick brain microtubules

Molecular Weight: 57kDa

Positive Control: Ls174T, MAD109 cells; skin or lung

Cellular Localization: Cytoplasmic Ab-2 causes the 10nm filaments to collapse into large lateral aggregates collecting in the cell periphery or tight juxtanuclear caps. It does not block microtubule assembly. It does not inhibit polymerization or depolymerization of platelet tubulin in vitro. It blocks (by 70-80%) the ability of tubulin dimers (with GppNHp bound) to promote a stable inhibition of adenylyl cyclase.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Electron Microscopy


USA: RUO; Int'l: RUO