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Thermo Scientific™ Lab Vision™ Tropomyosin Ab-1, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ Tropomyosin Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS1256PABX

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Catalog No. MS1256PABX

  • / Each
 

Description & Specifications

Specifications

Regulatory Status RUO
Clone CH1
Cross Reactivity Chicken
Cross Reactivity Human
Cross Reactivity Rat
Immunogen Tropomyosin protein purified from chicken embryo fibroblasts (CEF) and chicken leg, heart, and gizzard
Isotype IgG2a kappa
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Host Species Mouse
Quantity 200µL
Format Concentrated
Antigen Tropomyosin Ab-1
Conjugate Unlabeled
Classification Monoclonal
Formulation Ab without BSA/Azide (Frozen)
Type Primary
Research Discipline Muscle Biology
Concentration 1mg/mL

Provide accurate, reproducible results with the Thermo Scientific™ Tropomyosin Ab-1, Mouse Monoclonal Antibody.

Tropomyosin is a dimeric coiled-coil protein that binds along the length of actin filaments. It is associated with the thin filaments of muscle cells and the microfilaments of nonmuscle cells. Chicken embryo fibroblasts (CEF) contain five isoforms of tropomyosin (a, b, 1, 2, and 3), identified as such by their different apparent molecular masses after separation by SDS-PAGE, but similar biochemical properties, such as resistance to heat and organic solvents, the ability to bind to F-actin filaments, and the lack of proline and tryptophan.

Host Species: Mouse

Clone: CH1

Isotype: IgG1/κ

Species Reactivity: Human, Rat and Chicken. Others not known.

Epitope: Not determined

Immunogen: Tropomyosin protein purified from chicken embryo fibroblasts (CEF) and chicken leg, heart and gizzard

Positive Control: Skeletal or Cardiac muscle

Cellular Localization: Cytoplasmic Ab-1 reacts strongly with striated muscle forms of tropomyosin, including cardiac alpha-tropomyosin and skeletal alpha- and Beta-tropomyosins. ^

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not verified)
  • Immunofluorescence

Note:

USA: RUO; Int'l: RUO