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Alfa Aesar™ Tris(2-carboxyethyl)phosphine hydrochloride, 95%, 0.5M soln. in water

Chemical Identifiers

Chemical Name or Material Tris(2-carboxyethyl)phosphine hydrochloride
CAS 51805-45-9
Molecular Formula C9H15O6P·HCl
Linear Formula (HO2CCH2CH2)3P·HCl
Formula Weight 286.65
MDL Number MFCD00145469
UN Number UN3265
Synonym TCEP HCl
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAH51864AA

 
alfa aesar™
H51864AA
5mL CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAH51864AC

 
alfa aesar™
H51864AC
25mL CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAH51864AE

 
alfa aesar™
H51864AE
100mL CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description & Specifications

Specifications

Formula Weight 286.65
Chemical Name or Material Tris(2-carboxyethyl)phosphine hydrochloride
Assay 95%
Molecular Formula C9H15O6P·HCl
Linear Formula (HO2CCH2CH2)3P·HCl
MDL Number MFCD00145469
CAS 51805-45-9
UN Number UN3265
Synonym TCEP HCl
Health Hazard 1 Danger
Health Hazard 2 GHS H Statement
H314
Causes severe skin burns and eye damage.
Concentration 0.5M soln. in water
Quantity 5mL
Health Hazard 3 GHS P Statement
P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
Do not breathe dust/fume/gas/mist/vapors/spray.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
DOT Information Transport Hazard Class: 8; Packing Group: III; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.

Applications
Tris(2-carboxyethyl)phosphine hydrochloride is widely used as a reducing agent to reduce disulfide bonds in proteins and trans-4,5-dihydroxy-1,2-dithiane. It is involved in the reduction of sulfoxides, sulfonyl chlorides, N-oxides and azides. It plays an important role in the tissue homogenization process for RNA isolation. It acts as a chelating agent and forms complexes with various heavy metal ions such as Zn(II), Cd(II), Pb(II), and Ni(II). Furthermore, it is useful in the labeling of cysteine residues with maleimides.

Solubility
Miscible with water and methanol.

Notes
Air sensitive. Store in cool place. Incompatible with strong oxidizing agents

Safety and Handling

Danger

GHS P Statement
P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
Do not breathe dust/fume/gas/mist/vapors/spray.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H314
Causes severe skin burns and eye damage.