Please login to your online account to display your discounted pricing

Alfa Aesar™ (Trimethylsilyl)diazomethane, 2M in hexanes

$78.22 - $261.55

Chemical Identifiers

Chemical Name or Material (Trimethylsilyl)diazomethane
CAS 18107-18-1
Molecular Formula C4H10N2Si
Formula Weight 114.22g/mol
MDL Number MFCD00053946
UN Number UN3383
Beilstein 1902903
Synonym (Diazomethyl)trimethylsilane
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAH26744AA

 
alfa aesar™
H26744-AA
5mL Each for $78.22

AAH26744AC

 
alfa aesar™
H26744-AC
25mL Each for $261.55

AAH26744AE

 
alfa aesar™
H26744-AE
100mL CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description & Specifications

Specifications

Concentration 2M in hexanes
Quantity 5mL
Flash Point −23°C (−10°F)
Chemical Name or Material (Trimethylsilyl)diazomethane
CAS 18107-18-1
Molecular Formula C4H10N2Si
Formula Weight 114.22g/mol
MDL Number MFCD00053946
UN Number UN3383
Beilstein 1902903
Synonym (Diazomethyl)trimethylsilane
Health Hazard 1 Danger
Health Hazard 2 GHS H Statement
H225-H331-H350-H304-H361-H373-H315-H336
Highly flammable liquid and vapor.
Toxic if inhaled.
May cause cancer.
May be fatal if swallowed and enters airways.
Suspected of damaging fertility or the unborn child.
May cause damage to organs through prolonged or repeated exposure.
Causes skin irritation.
May cause drowsiness or dizziness.
Health Hazard 3 GHS P Statement
P210-P260-P301+P310-P303+P361+P353-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
Do not breathe dust/fume/gas/mist/vapors/spray.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
DOT Information Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: TOXIC BY INHALATION LIQUID, FLAMMABLE, N.O.S.

Applications
(Trimethylsilyl)diazomethane is used as a methylating agent in organic chemistry. It is utilized in Gas Chromatography- Mass-Spectrometry (GC-MS) for the analysis of various carboxylic compounds. It is involved as a reagent in the Doyle-Kirmse reaction with allyl sulfides and allyl amines. It is considered and used as a less-explosive replacement fordiazomethane. It is also used as a reactant for Unnatural alfa-amino acid derivatives containing gem-bisphosphonates through Michael addition reaction, imidazolo[2,1-b]benzothiazole derivatives and aigialomycin D analogues.

Solubility
Immiscible with water. Miscible with organic solvents.

Notes
(Trimethylsilyl)diazomethane (TMSD) in alcoholic solvents under acidic or basic conditions can lead to the formation of diazomethane. TMSD is under review by the National Toxicological Program for potential inhalation hazards.Incompatible with oxidizing agents, chlorine, fluorine and perchlorates.

Safety and Handling

Danger

GHS P Statement
P210-P260-P301+P310-P303+P361+P353-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
Do not breathe dust/fume/gas/mist/vapors/spray.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H225-H331-H350-H304-H361-H373-H315-H336
Highly flammable liquid and vapor.
Toxic if inhaled.
May cause cancer.
May be fatal if swallowed and enters airways.
Suspected of damaging fertility or the unborn child.
May cause damage to organs through prolonged or repeated exposure.
Causes skin irritation.
May cause drowsiness or dizziness.