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Alfa Aesar™ Trimethylacetyl chloride, 98+%

Chemical Identifiers

Chemical Name or Material Trimethylacetyl chloride
CAS 3282-30-2
Molecular Formula (CH3)3CCOCl
Formula Weight 120.58g/mol
MDL Number MFCD00000709
UN Number UN2438
Beilstein 385668
Synonym Pivaloyl chloride
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAA150510F

 
alfa aesar™
A15051-0F
2500mL CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAA15051AP

 
alfa aesar™
A15051-AP
500mL CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description & Specifications

Specifications

Melting Point −57°C
Boiling Point 105° to 106°C
Quantity 2500mL
Flash Point 8°C (46°F)
Odor Pungent
Chemical Name or Material Trimethylacetyl chloride
CAS 3282-30-2
Assay ≥98%
Molecular Formula (CH3)3CCOCl
Formula Weight 120.58g/mol
MDL Number MFCD00000709
UN Number UN2438
Beilstein 385668
Synonym Pivaloyl chloride
Health Hazard 1 Danger
Health Hazard 2 GHS H Statement
H225-H330-H314-H318-H302
Highly flammable liquid and vapour.
Fatal if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if swallowed.
Health Hazard 3 GHS P Statement
P210-P303+P361+P353-P304+P340-P305+P351+P338-P320-P330-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Specific treatment is urgent (see label).
Rinse mouth.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
DOT Information Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: TRIMETHYLACETYL CHLORIDE
TSCA TSCA

Applications
Trimethylacetyl chloride is used as a precursor in the preparation of tert-butyl peroxypivalate, guttiferon A derivatives, which is potential for the treatment of malaria. It is used as a raw material in the production of synthetic acidamide medicament and phenol ester medicament. In addition to this, it is used for the synthesis of active pharmaceutical ingredients such as aminobenzylpenicilin, cephalexin, cefazolin, dipivefrin and dipivalyl epinephrine. It is also used in heavy polymerization, N-acylating agent for amines, Schiff bases, pyrrolidinones as well as an O-acylating agent for alcohols, lactones and saccharides.

Solubility
Miscible with acetonitrile.

Notes
Moisture sensitive. Incompatible withalcohols, oxidizing agents and strong bases.

Safety and Handling

Danger

GHS P Statement
P210-P303+P361+P353-P304+P340-P305+P351+P338-P320-P330-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Specific treatment is urgent (see label).
Rinse mouth.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H225-H330-H314-H318-H302
Highly flammable liquid and vapour.
Fatal if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if swallowed.