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Trimethylacetyl chloride, 98+%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals A150510F
Description
Trimethylacetyl chloride is used as a precursor in the preparation of tert-butyl peroxypivalate, guttiferon A derivatives, which is potential for the treatment of malaria. It is used as a raw material in the production of synthetic acidamide medicament and phenol ester medicament. In addition to this, it is used for the synthesis of active pharmaceutical ingredients such as aminobenzylpenicilin, cephalexin, cefazolin, dipivefrin and dipivalyl epinephrine. It is also used in heavy polymerization, N-acylating agent for amines, Schiff bases, pyrrolidinones as well as an O-acylating agent for alcohols, lactones and saccharides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsTrimethylacetyl chloride is used as a precursor in the preparation of tert-butyl peroxypivalate, guttiferon A derivatives, which is potential for the treatment of malaria. It is used as a raw material in the production of synthetic acidamide medicament and phenol ester medicament. In addition to this, it is used for the synthesis of active pharmaceutical ingredients such as aminobenzylpenicilin, cephalexin, cefazolin, dipivefrin and dipivalyl epinephrine. It is also used in heavy polymerization, N-acylating agent for amines, Schiff bases, pyrrolidinones as well as an O-acylating agent for alcohols, lactones and saccharides.
Solubility
Miscible with acetonitrile.
Notes
Moisture sensitive. Incompatible withalcohols, oxidizing agents and strong bases.
Specifications
| Trimethylacetyl chloride | |
| -57°C | |
| 105°C to 106°C | |
| Pungent | |
| 1.412 | |
| 2500 mL | |
| 385668 | |
| pivaloyl chloride, trimethylacetyl chloride, propanoyl chloride, 2,2-dimethyl, pivalyl chloride, pivaloylchloride, 2,2-dimethylpropionyl chloride, pivalic acid chloride, pivalolyl chloride, unii-jq82j0o21t, 2,2-dimethylpropionylchloride | |
| JVSFQJZRHXAUGT-UHFFFAOYSA-N | |
| 2,2-dimethylpropanoyl chloride | |
| 62493 | |
| ≥98% |
| 3282-30-2 | |
| 0.985 | |
| 8°C (46°F) | |
| C5H9ClO | |
| MFCD00000709 | |
| UN2438 | |
| Moisture sensitive | |
| Miscible with acetonitrile. | |
| CC(C)(C)C(Cl)=O | |
| 120.58 | |
| 120.58 |
Chemical Identifiers
| 3282-30-2 | |
| 120.58 | |
| JVSFQJZRHXAUGT-UHFFFAOYSA-N | |
| 62493 | |
| CC(C)(C)C(Cl)=O |
| C5H9ClO | |
| MFCD00000709 | |
| pivaloyl chloride, trimethylacetyl chloride, propanoyl chloride, 2,2-dimethyl, pivalyl chloride, pivaloylchloride, 2,2-dimethylpropionyl chloride, pivalic acid chloride, pivalolyl chloride, unii-jq82j0o21t, 2,2-dimethylpropionylchloride | |
| 2,2-dimethylpropanoyl chloride |
Safety and Handling
GHS H Statement
H225-H330-H314-H318-H302
Highly flammable liquid and vapour.
Fatal if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if swallowed.
P210-P233-P234-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P390-P501c
H225-H290-H302-H314-H330
DOTInformation : Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: TRIMETHYLACETYL CHLORIDE
EINECSNumber : 221-921-6
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only