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Alfa Aesar™ Trimethylacetic anhydride, 99%

Chemical Identifiers

Chemical Name or Material Trimethylacetic anhydride
CAS 1538-75-6
Molecular Formula C10H18O3
Linear Formula ((CH3)3CCO)2O
Formula Weight 186.25
MDL Number MFCD00008842
UN Number UN3265
Beilstein 386552
Synonym Pivalic anhydride
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAB2298314

  SDS
alfa aesar™
B2298314
25g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAB2298336

  SDS
alfa aesar™
B2298336
500g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAB2298322

  SDS
alfa aesar™
B2298322
100g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description & Specifications

Specifications

Formula Weight 186.25
Odor Unpleasant
Health Hazard 2 GHS H Statement
H314-H318-H227
Causes severe skin burns and eye damage.
Causes serious eye damage.
Combustible liquid.
DOT Information Transport Hazard Class: 8; Packing Group: III; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
Molecular Formula C10H18O3
Linear Formula ((CH3)3CCO)2O
CAS 1538-75-6
MDL Number MFCD00008842
Health Hazard 3 GHS P Statement
P280-P305+P351+P338-P309-P310
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF exposed or if you feel unwell: Immediately call a POISON CENTER or doctor/physician.
Chemical Name or Material Trimethylacetic anhydride
Synonym Pivalic anhydride
Health Hazard 1 Danger
Beilstein 386552
Flash Point 63°C (145°F)
Assay 99%
UN Number UN3265
Quantity 25g
TSCA TSCA
Boiling Point 193°C

Applications
Trimethylacetic anhydride is used as acylation and esterification reagents. It is involved in acylation and esterification reactions with anilines and phenols. It is also used in solid-phase oligonucleotide synthesis and in the kinetic resolution of racemic 2-hydroxy-gamma-butyrolactones with diphenylacetic acid. It is also employed in the production of cyano-4, N-tert-butyloxycarbonyl piperidine.

Solubility
Miscible with acetonitrile.

Notes
Moisture sensitive. Incompatible with strong oxidizing agents, strong acids, strong bases and strong reducing agents.

Safety and Handling

Danger

GHS P Statement
P280-P305+P351+P338-P309-P310
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF exposed or if you feel unwell: Immediately call a POISON CENTER or doctor/physician.

GHS H Statement
H314-H318-H227
Causes severe skin burns and eye damage.
Causes serious eye damage.
Combustible liquid.