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Trimethylacetic anhydride, 99%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals B2298314
Description
Trimethylacetic anhydride is used as acylation and esterification reagents. It is involved in acylation and esterification reactions with anilines and phenols. It is also used in solid-phase oligonucleotide synthesis and in the kinetic resolution of racemic 2-hydroxy-gamma-butyrolactones with diphenylacetic acid. It is also employed in the production of cyano-4, N-tert-butyloxycarbonyl piperidine.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsTrimethylacetic anhydride is used as acylation and esterification reagents. It is involved in acylation and esterification reactions with anilines and phenols. It is also used in solid-phase oligonucleotide synthesis and in the kinetic resolution of racemic 2-hydroxy-gamma-butyrolactones with diphenylacetic acid. It is also employed in the production of cyano-4, N-tert-butyloxycarbonyl piperidine.
Solubility
Miscible with acetonitrile.
Notes
Moisture sensitive. Incompatible with strong oxidizing agents, strong acids, strong bases and strong reducing agents.
Specifications
| Trimethylacetic anhydride | |
| 0.918 | |
| 63°C (145°F) | |
| C10H18O3 | |
| ((CH3)3CCO)2O | |
| 25 g | |
| 386552 | |
| pivalic anhydride, trimethylacetic anhydride, 2,2-dimethylpropionic anhydride, propanoic acid, 2,2-dimethyl-, anhydride, pivalic anydride, 2,2-dimethylpropanoic anhydride, trimethylacetic acid anhydride, propanoic acid, 2,2-dimethyl-, 1,1'-anhydride, trimethylaceticanhydride, bispivalic anhydride | |
| PGZVFRAEAAXREB-UHFFFAOYSA-N | |
| 2,2-dimethylpropanoyl 2,2-dimethylpropanoate | |
| 15234 | |
| 99% |
| 1538-75-6 | |
| 193°C | |
| Unpleasant | |
| 1.409 | |
| MFCD00008842 | |
| UN3265 | |
| Moisture sensitive | |
| Miscible with acetonitrile. | |
| CC(C)(C)C(=O)OC(=O)C(C)(C)C | |
| 186.25 | |
| 186.25 |
Chemical Identifiers
| 1538-75-6 | |
| 186.25 | |
| PGZVFRAEAAXREB-UHFFFAOYSA-N | |
| 15234 | |
| CC(C)(C)C(=O)OC(=O)C(C)(C)C |
| C10H18O3 | |
| MFCD00008842 | |
| pivalic anhydride, trimethylacetic anhydride, 2,2-dimethylpropionic anhydride, propanoic acid, 2,2-dimethyl-, anhydride, pivalic anydride, 2,2-dimethylpropanoic anhydride, trimethylacetic acid anhydride, propanoic acid, 2,2-dimethyl-, 1,1'-anhydride, trimethylaceticanhydride, bispivalic anhydride | |
| 2,2-dimethylpropanoyl 2,2-dimethylpropanoate |
Safety and Handling
GHS H Statement
H314-H318-H227
Causes severe skin burns and eye damage.
Causes serious eye damage.
Combustible liquid.
P210-P233-P235-P240-P241-P242-P243-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
H226-H314-H335
DOTInformation : Hazard Class: 8; Packaging Group: II
EINECSNumber : 216-263-1
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only