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Thermo Scientific Chemicals Trifluoroacetic acid, biochemical grade, 99.5+%

Supplier:  Thermo Scientific Chemicals A1436530

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Catalog No. AAA1436530



Description

Description

Used to cleave peptide blocking groupsThe combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Used to cleave peptide blocking groupsThe combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.

Solubility
Miscible with ether, acetone, ethanol, benzene, hexane and carbon tetrachloride.

Notes
Trifluoroacetic acid (TFA) is a stable, hygroscopic, volatile and low-boiling organic acid. Storage in a cool place is recommended.
Specifications

Specifications

Trifluoroacetic acid
76-05-1
C2HF3O2
UN2699
14,9681
Miscible with ether,acetone,ethanol,benzene,hexane and carbon tetrachloride.
OC(=O)C(F)(F)F
114.02
CHEBI:45892
≥99.5%
1.48
Pungent
Hygroscopic
-15°C
72°C to 73°C
MFCD00004169
742035
trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoroacetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova
DTQVDTLACAAQTR-UHFFFAOYSA-N
trifluoroacetic acid
6422
114.02
Biochemical
250 g
1.284

Chemical Identifiers

76-05-1
114.02
DTQVDTLACAAQTR-UHFFFAOYSA-N
6422
trifluoroacetic acid
C2HF3O2
MFCD00004169
trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoroacetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova
CHEBI:45892
OC(=O)C(F)(F)F
Safety and Handling

Safety and Handling

GHS H Statement
H314-H332
Causes severe skin burns and eye damage.
Harmful if inhaled.

P234-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P390-P501c

H290-H314-H332-H335

DOTInformation : Transport Hazard Class: 8; Packing Group: I; Proper Shipping Name: TRIFLUOROACETIC ACID

EINECSNumber : 200-929-3

RTECSNumber : AJ9625000

TSCA : Yes

Recommended Storage : Ambient temperatures

SDS
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