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Trifluoroacetic Acid, 99%, Alfa Aesar™

Solvent, catalyst, strong non-oxidizing acid

$56.20 - $691.61

Chemical Identifiers

Chemical Name or Material Trifluoroacetic Acid
CAS 76-05-1
Physical Form Liquid
Assay Percent Range 99%
Molecular Formula CF3CO2H
Formula Weight 114.02
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAA1219822

  SDS
alfa aesar
A1219822*
100g Each for $56.20

AAA1219836

  SDS
alfa aesar
A1219836
500g Each for $173.28

AAA121980E

  SDS
alfa aesar
A121980E
2500g Each for $691.61
Description & Specifications

Specifications

Formula Weight 114.02
Quantity 100g
Boiling Point 72° to 73°C
Melting Point −15°C (5°F)
Physical Form Liquid
Density 1.480
Chemical Name or Material Trifluoroacetic Acid
CAS 76-05-1
Molecular Formula CF3CO2H
Assay Percent Range 99%
Storage Note 1 Hygroscopic

Applications
The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.

Solubility
Miscible with ether, acetone, ethanol, benzene, hexane, and CCl4

Notes
Trifluoroacetic acid (TFA) is a stable, hygroscopic, volatile and low-boiling organic acid. Storage in a cool place is recommended.

Safety and Handling

Hygroscopic