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Trifluoroacetic Acid, 99%, Alfa Aesar™

Solvent, catalyst, strong non-oxidizing acid

$56.43 - $686.22

Chemical Identifiers

Chemical Name or Material Trifluoroacetic Acid
CAS 76-05-1
Physical Form Liquid
Assay Percent Range 99%
Molecular Formula CF3CO2H
Formula Weight 114.02g/mol
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAA1219822

 
alfa aesar
A12198-22
100g Each for $56.43

AAA1219836

 
alfa aesar
A12198-36
500g Each for $174.74

AAA121980E

 
alfa aesar
A12198-0E
2500g Each for $686.22
Description & Specifications

Specifications

Density 1.480
Melting Point −15°C (5°F)
Boiling Point 72° to 73°C
Quantity 100g
Chemical Name or Material Trifluoroacetic Acid
CAS 76-05-1
Physical Form Liquid
Assay Percent Range 99%
Molecular Formula CF3CO2H
Formula Weight 114.02g/mol
Storage Note 1 Hygroscopic

Applications
The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.

Solubility
Miscible with ether, acetone, ethanol, benzene, hexane, and CCl4

Notes
Trifluoroacetic acid (TFA) is a stable, hygroscopic, volatile and low-boiling organic acid. Storage in a cool place is recommended.

Safety and Handling

Hygroscopic