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Alfa Aesar™ Triethyl methanetricarboxylate, 98%

Manufacturer:  Alfa Aesar™ L0835614

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Catalog No. AAL0835614



Description

Description

Applications
Methanetricarboxylates have been used as ″blocked″ malonic esters, restricting reaction with alkyl halides to monoalkylation. The unwanted carboxyl group can be removed by treatment with Na alkoxide, LDA or BCl3. Provides a useful 2-carbon chain extension method that adds to Michael acceptors under phase-transfer conditions. Triethyl Methanetricarboxylate is used in the synthesis of novel inhibitors of Hsp90. It is also used in the preparation of novel dihydroquinoline-3-carboxylic acids that function as HIV-1 integrase inhibitors.

Solubility
Insoluble in water.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
Specifications

Specifications

Triethyl methanetricarboxylate
253°C
25g
C10H16O6
1793645
AGZPNUZBDCYTBB-UHFFFAOYSA-N
triethyl methanetricarboxylate
80471
98%
>110°C (230°F)
26°C to 29°C
6279-86-3
MFCD00009150
2-ethoxycarbonyl-malonic acid diethyl ester
CCOC(=O)C(C(=O)OCC)C(=O)OCC
232.232
232.23

Chemical Identifiers

6279-86-3
232.232
AGZPNUZBDCYTBB-UHFFFAOYSA-N
80471
CCOC(=O)C(C(=O)OCC)C(=O)OCC
C10H16O6
MFCD00009150
2-ethoxycarbonyl-malonic acid diethyl ester
triethyl methanetricarboxylate
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