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Trefoil Factor 3 Mouse anti-Mouse, Rat, Biotin, Clone: 5UCLNT3, eBioscience™

Mouse Monoclonal Antibody

$129.05 - $346.55

Specifications

Antigen Trefoil Factor 3
Clone 5UCLNT3
Host Species Mouse
Gene Alias TFF3
Species Reactivity Mouse, Rat
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122545

 
affymetrix
13475880
25μg Each for $129.05

501122546

 
affymetrix
13475882
100μg Each for $346.55
Description & Specifications

Specifications

Antigen Trefoil Factor 3
Clone 5UCLNT3
Host Species Mouse
Gene Alias TFF3
Species Reactivity Mouse, Rat
Applications Immunohistochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Microscopy
Applications Western Blotting
Regulatory Status RUO
Conjugate Biotin
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The monoclonal antibody 5UCLNT3 recognizes mouse and rat Trefoil Factor 3. Trefoil Factor 3 (TFF3) is a member of the trefoil family, which are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. TFF3 is a small peptide hormone secreted by mucus-producing cells and by epithelial cells of multiple tissues, including the gastrointestinal tract, kidney, and breast. TFF3 plays an essential role in both mucosal surface maintenance and restitution. TFF3 facilitates restoration of the intestinal epithelium as a protective barrier against injury by inhibiting apoptosis and promoting survival and migration of epithelial cells. TFF3 also plays a role in inducing airway epithelial ciliated cell differentiation. Levels of TFF3 change after renal injury and urinary levels can be used as a biomarker for kidney tubular injury. TFF3 may also play a role in breast tumor progression and tumor cell dissemination.