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Thermo Scientific™ Lab Vision™ Transglutaminase II Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Transglutaminase II Ab-1, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS224P1ABX

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Catalog No. MS224P1ABX


 

Specifications

Description

Provide accurate, reproducible results with the Thermo Scientific™ Transglutaminase II Ab-1, Mouse Monoclonal Antibody.

Transglutaminase II catalyzes calcium-dependent post-translational modification of proteins by formation of an isopeptide bond within or between polypeptide chains. It is also known as TGC, tTG, type II-, Gh, cytosolic-, liver-, endothelial-, erythrocyte-, cellular-transglutaminase. Different tissues and cell types express varying amounts of tissue transglutaminase with a markedly hugh expression in rheumatoid lesions. It is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.

Host Species: Mouse

Clone: CUB 7402

Isotype: IgG1/κ

Species Reactivity: Human, Dog, Rabbit and Guinea Pig. Does not react with mouse and rat. Others not known.

Epitope: aa 447-478

Immunogen: Purified guinea pig liver TGase II

Molecular Weight: 77-85kDa

Positive Control: HUVEC cells, Breast CA

Cellular Localization: Cytoplasm, membrane and extracellular matrix Ab-1 inhibits the TGase II activity.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Affinity Purification
  • Biological Blockade

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

Transglutaminase II Ab-1
Monoclonal
1mg/mL
Ab without BSA/Azide (Frozen)
Murine
IgG2a kappa
RUO
Primary
Canine,Guinea Pig,Human,Rabbit
Immunofluorescence,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting
CUB 7402
Unlabeled
Concentrated
Purified guinea pig liver TGase II
100μL
Neuroscience
Monoclonal