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Thermo Scientific™ Lab Vision™ Transglutaminase II Ab-1, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ Transglutaminase II Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS224P1ABX

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Catalog No. MS224P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen Transglutaminase II Ab-1
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone CUB 7402
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Canine
Cross Reactivity Guinea Pig
Cross Reactivity Human
Cross Reactivity Rabbit
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Mouse
Immunogen Purified guinea pig liver TGase II
Isotype IgG2a kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline Neuroscience
Type Primary

Provide accurate, reproducible results with the Thermo Scientific™ Transglutaminase II Ab-1, Mouse Monoclonal Antibody.

Transglutaminase II catalyzes calcium-dependent post-translational modification of proteins by formation of an isopeptide bond within or between polypeptide chains. It is also known as TGC, tTG, type II-, Gh, cytosolic-, liver-, endothelial-, erythrocyte-, cellular-transglutaminase. Different tissues and cell types express varying amounts of tissue transglutaminase with a markedly hugh expression in rheumatoid lesions. It is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.

Host Species: Mouse

Clone: CUB 7402

Isotype: IgG1/κ

Species Reactivity: Human, Dog, Rabbit and Guinea Pig. Does not react with mouse and rat. Others not known.

Epitope: aa 447-478

Immunogen: Purified guinea pig liver TGase II

Molecular Weight: 77-85kDa

Positive Control: HUVEC cells, Breast CA

Cellular Localization: Cytoplasm, membrane and extracellular matrix Ab-1 inhibits the TGase II activity.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Affinity Purification
  • Biological Blockade

Note:

USA: RUO; Int'l: RUO