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Thermo Scientific™ Lab Vision™ Transforming Growth Factor α (TGFα) Ab-1, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ Transforming Growth Factor α (TGFα) Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS670P1ABX

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Catalog No. MS670P1ABX

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Description & Specifications

Specifications

Antigen Transforming Growth Factor alpha (TGFalpha) Ab-1
Applications Western Blot
Classification Monoclonal
Clone MF9
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Concentrated
Host Species Murine
Immunogen A 17-amino acid synthetic peptide from the carboxyl-terminus of Rat TGFalpha
Isotype IgG2a kappa
Quantity 100μL
Regulatory Status RUO
Research Discipline Signal Transduction
Type Primary
Monoclonal or Polyclonal Monoclonal
Target Species Bovine
Target Species Human
Target Species Murine
Target Species Rat

Provide accurate, reproducible results with the Thermo Scientific™ Transforming Growth Factor α (TGFα) Ab-1, Mouse Monoclonal Antibody.

TGFα (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

Host Species: Mouse

Clone: MF9

Isotype: IgG1/κ

Species Reactivity: Human, Cow, Rat and Mouse. Others not known.

Epitope: C-terminal

Immunogen: A 17-amino acid synthetic peptide from the carboxyl-terminus of rat TGFα

Molecular Weight: 6kDa

Positive Control: Recombinant TGFα protein, A2058 cells

Cellular Localization: Cytoplasmic Ab-1 shows no cross-reaction with EGF and the neuropeptide synenkephalin. Ab-1 is excellent for staining of formalin-fixed, paraffin-embedded tissues. The staining with Ab-1 is completely blocked by the peptide used for raising this antibody.

Recommended for:

  • Western Blotting

Note:

USA: RUO; Int'l: RUO