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TRA-1-81 (podocalyxin) Mouse anti-Human, Clone: TRA-1-81, eBioscience™

Mouse Monoclonal Antibody

$158.05 - $346.55

Specifications

Antigen TRA-1-81 (podocalyxin)
Clone TRA-1-81
Host Species Mouse
Species Reactivity Human
Applications Flow Cytometry
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013756

 
affymetrix
14-8883-80
25μg Each for $158.05

5013757

 
affymetrix
14-8883-82
100μg Each for $346.55
Description & Specifications

Specifications

Antigen TRA-1-81 (podocalyxin)
Clone TRA-1-81
Host Species Mouse
Species Reactivity Human
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunoprecipitation
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, contains carrier protein/stabilizer if necessary
Concentration 0.5mg/mL

The TRA-1-81 antibody recognizes a protein expressed on undifferentiated human embryonic stem cells (ES), embryonic carcinoma cells (EC), and embryonic germ cells (EG). Like other stem cell specific markers, the epitope recognized by the TRA-1-81 antibody is lost upon cell differentiation. The TRA-1-81 epitope is resistant to neuraminidase digestion, unlike the epitope recognized by the related TRA-1-60 antibody. The TRA-1-81 antibody is known to specifically recognize a carbohydrate epitope on a keratan sulfated glycoprotein recently identified as podocalyxin, a member of the CD34-related family of sialomucins. Podocalyxin is a transmembrane glycoprotein originally identified on epithelial glomerular cells known as podocytes, and the protein has also been implicated in the development of aggressiveness in a variety of cancers, including breast and prostate cancer.