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TRA-1-60 (podocalyxin) Mouse anti-Human, Clone: TRA-1-60, eBioscience™

Mouse Monoclonal Antibody

$143.88 - $315.48

Specifications

Antigen TRA-1-60 (podocalyxin)
Clone TRA-1-60
Host Species Murine
Applications Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot
Regulatory Status RUO
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013752 Life Technologies
LS14886380
25μg Each for $143.88
5013753 Life Technologies
LS14886382
100μg Each for $315.48
Specifications

Description

The TRA-1-60 antibody recognizes a protein expressed on undifferentiated human embryonic stem cells (ES), embyronal carcinoma cells (EC), and embryonic germ cells (EG). Like other stem cell specific markers, the epitope recognized by the TRA-1-60 antibody is lost upon cell differentiation. Contrary to early reports that the TRA-1-60 epitope can be destroyed by neuraminidase digestion, new strudies have shown that TRA-1-60 recognizes a neurominidase resistent antigen. The TRA-1-60 antibody is known to specifically recognize a carbohydrate epitope on a keratan sulfated glycoprotein recently identified as podocalyxin, a member of the CD34-related family of sialomucins. Podocalyxin is a transmembrane glycoprotein originally identified on epithelial glomerular cells known as podocytes, and the protein has also been implicated in the development of aggressiveness in a variety of cancers, including breast and prostate cancer.
Description & Specifications

Specifications

TRA-1-60 (podocalyxin)
Murine
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, contains carrier protein/stabilizer if necessary
TRA-1-60
Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL