Please login to your online account to display your discounted pricing

TRA-1-60 (podocalyxin) Mouse anti-Human, Clone: TRA-1-60, eBioscience™

Mouse Monoclonal Antibody

$158.05 - $346.55

Specifications

Antigen TRA-1-60 (podocalyxin)
Clone TRA-1-60
Host Species Mouse
Species Reactivity Human
Applications Flow Cytometry
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013752

 
affymetrix
14886380
25μg Each for $158.05

5013753

 
affymetrix
14886382
100μg Each for $346.55
Description & Specifications

Specifications

Antigen TRA-1-60 (podocalyxin)
Clone TRA-1-60
Host Species Mouse
Species Reactivity Human
Applications Flow Cytometry
Applications Immunohistochemistry
Applications Immunoprecipitation
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, contains carrier protein/stabilizer if necessary
Concentration 0.5mg/mL

The TRA-1-60 antibody recognizes a protein expressed on undifferentiated human embryonic stem cells (ES), embyronal carcinoma cells (EC), and embryonic germ cells (EG). Like other stem cell specific markers, the epitope recognized by the TRA-1-60 antibody is lost upon cell differentiation. Contrary to early reports that the TRA-1-60 epitope can be destroyed by neuraminidase digestion, new strudies have shown that TRA-1-60 recognizes a neurominidase resistent antigen. The TRA-1-60 antibody is known to specifically recognize a carbohydrate epitope on a keratan sulfated glycoprotein recently identified as podocalyxin, a member of the CD34-related family of sialomucins. Podocalyxin is a transmembrane glycoprotein originally identified on epithelial glomerular cells known as podocytes, and the protein has also been implicated in the development of aggressiveness in a variety of cancers, including breast and prostate cancer.