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TOX Rat anti-Mouse, Clone: TXRX10, eBioscience™

Rat Monoclonal Antibody

$129.05 - $259.55

Specifications

Antigen TOX
Clone TXRX10
Host Species Rat
Gene Alias Thymocyte selection-associated HMG box protein
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013483

 
affymetrix
14-6502-80
25μg Each for $129.05

5013484

 
affymetrix
14650282
100μg Each for $259.55
Description & Specifications

Specifications

Antigen TOX
Clone TXRX10
Host Species Rat
Gene Alias Thymocyte selection-associated HMG box protein
Species Reactivity Mouse
Applications Immunoprecipitation
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This TXRX10 monoclonal antibody reacts with human and mouse TOX, which is also known as Thymocyte selection-associated HMG box protein. This DNA-binding nuclear factor is expressed in thymocytes, T lymphocytes, NK cells, and lymphoid tissue-inducer (LTi) cells. TOX expression in thymocytes is upregulated during β-selection and positive selection. Studies using Tox knockout mice have demonstrated a critical role for TOX in CD4+ T cell development as a regulator of the CD4loCD8lo to CD4+CD8lo transition. Moreover, TOX has been shown to be involved in the development of NK and LTi cells. While its regulation remains unclear, TOX expression has been shown to be induced by calcineurin-mediated TCR signaling in thymocytes during positive selection.