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Thermo Scientific™ Lab Vision™ Topoisomerase II α Ab-1, Rabbit Polyclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ Topoisomerase II α Ab-1, Rabbit Polyclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  RB117P1ABX

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Catalog No. RB117P1ABX

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Description & Specifications

Specifications

Antigen Topoisomerase II alpha Ab-1
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Classification Polyclonal
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Rabbit
Immunogen A synthetic peptide, corresponding to aa 1513-1530 (RAKKPIKYLEESDEDDLF) from the C-terminus of human topoisomerase IIalpha
Isotype IgG
Quantity 500µL
Regulatory Status RUO
Research Discipline DNA Repair
Type Primary

Provide accurate, reproducible results with the Thermo Scientific™ Topoisomerase II α Ab-1, Rabbit Polyclonal Antibody.

Topo IIα plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Note that Ki67/M1B1 is also present in G1-phase. Topo IIα is also implicated in drug resistance of tumor cells.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human. Others not known.

Epitope: aa 1513-1530

Immunogen: A synthetic peptide, corresponding to aa 1513-1530 (RAKKPIKYLEESDEDDLF) from the C-terminus of human topoisomerase IIα

Molecular Weight: 170kDa

Positive Control: Raji cells or any exponentially growing cultured human cells

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)

Note:

USA: RUO; Int'l: RUO