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Tocris™ Topiramate

GluR5 antagonist; inhibits carbonic anhydrase (CA) II and IV

$116.01 - $488.83

Specifications

Product Type Topiramate
Inhibitors Topiramate
Molecular Weight 339.36
Purity >99
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Disclaimers:

For Research Use Only



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
362010R Tocris™
RDS362010
10mg Each for $116.01
362050R Tocris™
RDS362050
50mg Each for $488.83
Specifications

Description

Anticonvulsant. Antagonizes GluR5 kainate receptors (IC50 = 0.46μM), acts as a positive allosteric modulator of GABAA receptor-mediated currents, inhibits Nav channels (IC50 = 48.9μM) and inhibits L-type Ca2+ channels. Also inhibits carbonic anhydrase (CA) (Ki values are 0.1 and 0.2μM at rat CA II and CA IV respectively), which lowers intracellular neuronal pH.
  • Chemical Name: 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate
  • Formula: C12H21NO8S
  • CAS Number: 97240-79-4
  • Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
  • Purity: >99
Description & Specifications

Specifications

Topiramate
Topiramate
339.36
>99