Please login to your online account to display your discounted pricing

Tocris™ Topiramate

GluR5 antagonist; inhibits carbonic anhydrase (CA) II and IV

$114.38 - $481.95

Specifications

Product Type Topiramate
Inhibitors Topiramate
Molecular Weight 339.36
Purity >99
View More Specs

 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

362010R

 
tocris™
3620/10
10mg Each for $114.38

362050R

 
tocris™
3620/50
50mg Each for $481.95
Description & Specifications

Specifications

Product Type Topiramate
Inhibitors Topiramate
Molecular Weight 339.36
Purity >99

Anticonvulsant. Antagonizes GluR5 kainate receptors (IC50 = 0.46μM), acts as a positive allosteric modulator of GABAA receptor-mediated currents, inhibits Nav channels (IC50 = 48.9μM) and inhibits L-type Ca2+ channels. Also inhibits carbonic anhydrase (CA) (Ki values are 0.1 and 0.2μM at rat CA II and CA IV respectively), which lowers intracellular neuronal pH.

  • Chemical Name: 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate
  • Formula: C12H21NO8S
  • CAS Number: 97240-79-4
  • Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
  • Purity: >99