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Tocris™ TMCB

Dual-kinase inhibitor; inhibits CK2 and ERK8

$168.15 - $697.40

Specifications

Product Type TMCB
Inhibitors TMCB
Molecular Weight 534.82
Purity >98
View More Specs

Disclaimers:

For Research Use Only



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
367510R Tocris™
367510
10mg Each for $168.15
367550R Tocris™
367550
50mg Each for $697.40
Specifications

Description

Dual-kinase inhibitor; inhibits both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8) (IC50 = 0.50μM for both CK2 and ERK8). Displays selectivity for CK2 over protein kinases normally susceptible to CK2 inhibitors (Ki values are 0.25, 8.65, 11.90 and 15.25μM for CK2, PIM1, DYRK1a and HIPK2 respectively).
  • Chemical Name: 2-(4,5,6,7-Tetrabromo-2-(dimethylamino)-1H-benzo[d]imidazol-1-yl)acetic acid
  • Formula: C11H9Br4N3O2
  • CAS Number: 905105-89-7
  • Solubility: Soluble to 25mM in DMSO
  • Purity: >98
Description & Specifications

Specifications

TMCB
TMCB
534.82
>98