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Tocris™ TMCB

Dual-kinase inhibitor; inhibits CK2 and ERK8

$165.79 - $700.43

Specifications

Product Type TMCB
Inhibitors TMCB
Molecular Weight 534.82
Purity >98
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 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

367510R

 
tocris™
3675/10
10mg Each for $165.79

367550R

 
tocris™
3675/50
50mg Each for $700.43
Description & Specifications

Specifications

Product Type TMCB
Inhibitors TMCB
Molecular Weight 534.82
Purity >98

Dual-kinase inhibitor; inhibits both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8) (IC50 = 0.50μM for both CK2 and ERK8). Displays selectivity for CK2 over protein kinases normally susceptible to CK2 inhibitors (Ki values are 0.25, 8.65, 11.90 and 15.25μM for CK2, PIM1, DYRK1a and HIPK2 respectively).

  • Chemical Name: 2-(4,5,6,7-Tetrabromo-2-(dimethylamino)-1H-benzo[d]imidazol-1-yl)acetic acid
  • Formula: C11H9Br4N3O2
  • CAS Number: 905105-89-7
  • Solubility: Soluble to 25mM in DMSO
  • Purity: >98