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TL1A Mouse anti-Human, Mouse, PerCP-eFluor 710, Clone: Tandys1a, eBioscience™

Mouse Monoclonal Antibody

$170.28 - $421.08

Specifications

Antigen TL1A
Clone Tandys1a
Host Species Murine
Gene Alias TNFSF15, VEGI, Tumor necrosis factor ligand superfamily member 15
Applications Flow Cytometry,Flow Cytometry (Intracellular Staining)
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123913 Life Technologies
LS46791180
25μg Each for $170.28
501129469 Life Technologies
LS46791182
100μg Each for $421.08
Specifications

Description

The Tandys1a monoclonal antibody reacts with human and mouse TL1A (TNFSF15). TL1A is a member of the TNF ligand family and is expressed by endothelial cells, tissue macrophages, monocyte-derived dendritic cells, plasma cells and lamina propria-derived lymphocytes. Among peripheral blood cells, TL1A has been shown to be expressed predominantly by CD4+CCR9+ lymphocytes. Its expression has been shown to be induced by TNF alpha, IL-1 alpha and IFN gamma. TL1A binds DR3, which has been shown to be specifically upregulated in Th17 cells among CD4+ T cells. TL1A-deficient dendritic cells are weak in their ability to support Th17 cells in vitro and show decreased severity of EAE. In vivo, TL1A has been shown to be upregulated in tissue lymphocytes of Crohn’s Disease and ulcerative colitis patients.
Description & Specifications

Specifications

TL1A
Murine
Flow Cytometry,Flow Cytometry (Intracellular Staining)
PerCP-eFluor 710
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL
Tandys1a
TNFSF15, VEGI, Tumor necrosis factor ligand superfamily member 15
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer