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TL1A Mouse anti-Human, Mouse, PerCP-eFluor 710, Clone: Tandys1a, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $462.55

Specifications

Antigen TL1A
Clone Tandys1a
Host Species Mouse
Gene Alias TNFSF15, VEGI, Tumor necrosis factor ligand superfamily member 15
Species Reactivity Human, Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123913

 
affymetrix
46791180
25μg Each for $187.05

501129469

 
affymetrix
46-7911-82
100μg Each for $462.55
Description & Specifications

Specifications

Antigen TL1A
Clone Tandys1a
Host Species Mouse
Gene Alias TNFSF15, VEGI, Tumor necrosis factor ligand superfamily member 15
Species Reactivity Human, Mouse
Applications Flow Cytometry
Applications Flow Cytometry (Intracellular Staining)
Regulatory Status RUO
Conjugate PerCP-eFluor 710
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The Tandys1a monoclonal antibody reacts with human and mouse TL1A (TNFSF15). TL1A is a member of the TNF ligand family and is expressed by endothelial cells, tissue macrophages, monocyte-derived dendritic cells, plasma cells and lamina propria-derived lymphocytes. Among peripheral blood cells, TL1A has been shown to be expressed predominantly by CD4+CCR9+ lymphocytes. Its expression has been shown to be induced by TNF alpha, IL-1 alpha and IFN gamma. TL1A binds DR3, which has been shown to be specifically upregulated in Th17 cells among CD4+ T cells. TL1A-deficient dendritic cells are weak in their ability to support Th17 cells in vitro and show decreased severity of EAE. In vivo, TL1A has been shown to be upregulated in tissue lymphocytes of Crohn’s Disease and ulcerative colitis patients.