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TIMP-2 Ab-5 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ TIMP-2 Ab-5, Mouse Monoclonal Antibody.
Supplier: Thermo Fisher Scientific MS1485P1
Description
TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.Host Species: Mouse
Clone: 3A4
Isotype: IgG2a/κ
Species Reactivity: Human, Mouse, Rat, Rabbit, Cow and Guinea Ppig. Others not known.
Epitope: N-terminal
Immunogen: A synthetic peptide from the N-terminal region of human TIMP-2 protein
Molecular Weight: 21kDa
Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells; Pancreatic or colon CA
Cellular Localization: Cytoplasmic
Recommended for:
- Immunohistochemistry (Formalin/paraffin only)
- Western Blotting
- Immunoprecipitation (Not suitable)
Note:
USA: RUO; Int'l: RUO
Specifications
| TIMP-2 Ab-5 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 500 μL | |
| Proteases And Inhibitors | |
| Bovine, Guinea Pig, Human, Mouse, Rabbit, Rat | |
| IgG2a κ |
| Immunohistochemistry (Paraffin), Western Blot | |
| 3A4 | |
| Unconjugated | |
| A synthetic peptide from the N-terminal region of human TIMP-2 protein | |
| RUO | |
| Primary | |
| Concentrated |