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Thermo Scientific™ Lab Vision™ TIMP-2 Ab-5, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ TIMP-2 Ab-5, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS1485P1ABX

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Catalog No. MS1485P1ABX

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Description & Specifications

Specifications

Antigen TIMP-2 Ab-5
Applications Immunohistochemistry (Paraffin)
Applications Western Blotting
Classification Monoclonal
Clone 3A4
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Guinea Pig
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rabbit
Cross Reactivity Rat
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Mouse
Immunogen A synthetic peptide from the N-terminal region of human TIMP-2 protein
Isotype IgG2a kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline Proteases And Inhibitors
Type Primary

Provide accurate, reproducible results with the Thermo Scientific™ TIMP-2 Ab-5, Mouse Monoclonal Antibody.

TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Host Species: Mouse

Clone: 3A4

Isotype: IgG2a/κ

Species Reactivity: Human, Mouse, Rat, Rabbit, Cow and Guinea Ppig. Others not known.

Epitope: N-terminal

Immunogen: A synthetic peptide from the N-terminal region of human TIMP-2 protein

Molecular Weight: 21kDa

Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells; Pancreatic or colon CA

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin only)
  • Western Blotting
  • Immunoprecipitation (Not suitable)

Note:

USA: RUO; Int'l: RUO