Thermo Scientific™ Lab Vision™ TIMP-2 Ab-5, Mouse Monoclonal Antibody
Provide accurate, reproducible results with the Thermo Scientific™ TIMP-2 Ab-5, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS1485P1ABX
Provide accurate, reproducible results with the Thermo Scientific™ TIMP-2 Ab-5, Mouse Monoclonal Antibody.TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Host Species: Mouse
Species Reactivity: Human, Mouse, Rat, Rabbit, Cow and Guinea Ppig. Others not known.
Immunogen: A synthetic peptide from the N-terminal region of human TIMP-2 protein
Molecular Weight: 21kDa
Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells; Pancreatic or colon CA
Cellular Localization: Cytoplasmic
- Immunohistochemistry (Formalin/paraffin only)
- Western Blotting
- Immunoprecipitation (Not suitable)
USA: RUO; Int'l: RUO
|Ab without BSA/Azide (Frozen)|
|A synthetic peptide from the N-terminal region of human TIMP-2 protein|
|Proteases And Inhibitors|
|Immunohistochemistry (Paraffin),Western Blotting|