Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ TIMP-2 Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ TIMP-2 Ab-1, Mouse Monoclonal Antibody.

$254.00 - $1,505.84

Specifications

Antigen TIMP-2 Ab-1
Clone T2-101
Applications Immunoprecipitation
Applications Western Blotting
Applications Immunoprecipitation
View More Specs
Products
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity    

MS571B

 
thermo scientific™ lab vision™
MS-571-B
200�g/mL Biotin 1mL Each for $1,505.84

MS571B0

 
thermo scientific™ lab vision™
MS-571-B0
200�g/mL Biotin 100µL Each for $344.96

MS571B1

 
thermo scientific™ lab vision™
MS-571-B1
200�g/mL Biotin 500µL Each for $949.69

MS571P

 
thermo scientific™ lab vision™
MS-571-P
200�g/mL Unlabeled 1mL Each for $1,204.16

MS571P0

 
thermo scientific™ lab vision™
MS-571-P0
200�g/mL Unlabeled 100µL Each for $254.00

MS571P1

 
thermo scientific™ lab vision™
MS-571-P1
200�g/mL Unlabeled 500µL Each for $714.90

MS571P1ABX

 
thermo scientific™ lab vision™
MS571P1ABX
1mg/mL Unlabeled 100µL Each for $802.27

MS571PABX

 
thermo scientific™ lab vision™
MS-571-PABX
1mg/mL Unlabeled 200µL Each for $1,301.14
Description & Specifications

Specifications

Antigen TIMP-2 Ab-1
Clone T2-101
Applications Immunoprecipitation
Applications Western Blotting
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Regulatory Status RUO
Research Discipline Proteases And Inhibitors
Type Primary
Immunogen Native human pro-MMP-2/TIMP-2 complex purified from A2058 culture medium followed by purified human rTIMP-2
Isotype IgG1

Provide accurate, reproducible results with the Thermo Scientific™ TIMP-2 Ab-1, Mouse Monoclonal Antibody.

Tissue inhibitor of metalloproteinases-1 (TIMP-1) and Tissue inhibitor of metalloproteinases-2 (TIMP-2) have similar properties, specifically in inhibiting enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Host Species: Mouse

Clone: T2-101

Isotype: IgG1

Species Reactivity: Human. Does not react with mouse and rat. Others not known.

Epitope: aa 111-126. This epitope is not involved in binding of TIMP-2 to MMP-2

Immunogen: Native human pro-MMP-2/TIMP-2 complex purified from A2058 culture medium followed by purified human rTIMP-2

Molecular Weight: 21kDa

Positive Control: Conditioned, serum-free medium from (TPA-treated) human fetal lung cell line HFL-1

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Not suitable)
  • Immunoprecipitation (Native and denatured)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO

General References:

1. Hurskainen T, et. al. Human Pathology, 1996, 27(1):42-9.

2. Hurskainen T, et. al. Journal of Histochemistry and Cytochemistry, 1996, 44(12):1379-88.

3. Visscher DW, et. al. International Journal of Cancer, 1994, 59(3):339-44.

4. Hoyhtya M, et. al. International Journal of Cancer, 1994, 56(4):500-5.