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TIMP-1 Ab-2 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ TIMP-1 Ab-2, Mouse Monoclonal Antibody.
Supplier: Thermo Fisher Scientific MS608B1
Description
Tissue inhibitor of metalloproteinases-1 (TIMP-1) and Tissue inhibitor of metalloproteinases-2 (TIMP-2) are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-1 forms a complex of 1:1 stoichiometry with activated interstitial collagenase, activated stromelysin, active form of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A), and latent and active forms 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMPs inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.Host Species: Mouse
Clone: 102D1
Isotype: IgG1
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Recombinant human TIMP-1
Molecular Weight: 28.5kDa
Positive Control: Conditioned, serum-free medium from (TPA-treated) human fetal lung cell line HFL-1; Bladder, breast and ovarian CA
Cellular Localization: Cytoplasmic
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
Note:
USA: RUO; Int'l: RUO
Specifications
| TIMP-1 Ab-2 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 500 μL | |
| Proteases And Inhibitors | |
| Human | |
| IgG1 |
| Immunohistochemistry (Paraffin), Western Blot | |
| 102D1 | |
| Biotin | |
| Recombinant human TIMP-1 | |
| RUO | |
| Primary | |
| Concentrated |