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Thermo Scientific™ Lab Vision™ TIMP-1 Ab-2, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ TIMP-1 Ab-2, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS608P1ABX

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Catalog No. MS608P1ABX

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Description & Specifications

Specifications

Antigen TIMP-1 Ab-2
Applications Immunohistochemistry (Paraffin)
Applications Western Blotting
Classification Monoclonal
Clone 102D1
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Mouse
Immunogen Recombinant human TIMP-1
Isotype IgG1
Quantity 100µL
Regulatory Status RUO
Research Discipline Proteases And Inhibitors
Type Primary

Provide accurate, reproducible results with the Thermo Scientific™ TIMP-1 Ab-2, Mouse Monoclonal Antibody.

Tissue inhibitor of metalloproteinases-1 (TIMP-1) and Tissue inhibitor of metalloproteinases-2 (TIMP-2) are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-1 forms a complex of 1:1 stoichiometry with activated interstitial collagenase, activated stromelysin, active form of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A), and latent and active forms 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMPs inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Host Species: Mouse

Clone: 102D1

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human TIMP-1

Molecular Weight: 28.5kDa

Positive Control: Conditioned, serum-free medium from (TPA-treated) human fetal lung cell line HFL-1; Bladder, breast and ovarian CA

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO