Thermo Scientific™ Lab Vision™ TIMP-1 Ab-2, Mouse Monoclonal Antibody
Provide accurate, reproducible results with the Thermo Scientific™ TIMP-1 Ab-2, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS608P1ABX
Provide accurate, reproducible results with the Thermo Scientific™ TIMP-1 Ab-2, Mouse Monoclonal Antibody.Tissue inhibitor of metalloproteinases-1 (TIMP-1) and Tissue inhibitor of metalloproteinases-2 (TIMP-2) are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-1 forms a complex of 1:1 stoichiometry with activated interstitial collagenase, activated stromelysin, active form of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A), and latent and active forms 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMPs inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Host Species: Mouse
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Recombinant human TIMP-1
Molecular Weight: 28.5kDa
Positive Control: Conditioned, serum-free medium from (TPA-treated) human fetal lung cell line HFL-1; Bladder, breast and ovarian CA
Cellular Localization: Cytoplasmic
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
USA: RUO; Int'l: RUO
|Ab without BSA/Azide (Frozen)|
|Recombinant human TIMP-1|
|Proteases And Inhibitors|
|Immunohistochemistry (Paraffin),Western Blotting|