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tigit Mouse anti-Human, Clone: MBSA43, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

$143.55 - $506.05

Specifications

Antigen tigit
Clone MBSA43
Host Species Mouse
Gene Alias VSTM3, WUCAM
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014783

 
affymetrix
16950082
100μg Each for $143.55

5014784

 
affymetrix
16950085
500μg Each for $506.05
Description & Specifications

Specifications

Antigen tigit
Clone MBSA43
Host Species Mouse
Gene Alias VSTM3, WUCAM
Species Reactivity Human
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

The MBSA43 monoclonal antibody reacts with human T cell immunoreceptor with Ig and ITIM domains (TIGIT), which is also known as VSTM3 or WUCAM. This 26kDa protein is a member of the poliovirus receptor (PVR) family. The expression of TIGIT has been reported on NK cells, regulatory T cells, follicular T helper cells, memory CD4+ T cells, and CD8+ T cells, but it is not expressed on B cells or naïve CD4+ T cells. TIGIT may be upregulated on naïve CD4+ T cells upon activation. TIGIT can interact with certain members of the PVR and PVR-like families, including CD155, and also mediates the interaction of NK and T cells with antigen presenting cells, fibroblasts, and endothelial cells that express PVR and PVR-like proteins.

MBSA43 is reported to crossreact with Rhesus macaque.