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tigit Mouse anti-Human, Clone: MBSA43, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

$130.68 - $460.68

Specifications

Antigen tigit
Clone MBSA43
Host Species Murine
Gene Alias VSTM3, WUCAM
Applications Flow Cytometry,Functional Assay
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5014783 Life Technologies
LS16950082
100μg Each for $130.68
5014784 Life Technologies
LS16950085
500μg Each for $460.68
Specifications

Description

The MBSA43 monoclonal antibody reacts with human T cell immunoreceptor with Ig and ITIM domains (TIGIT), which is also known as VSTM3 or WUCAM. This 26kDa protein is a member of the poliovirus receptor (PVR) family. The expression of TIGIT has been reported on NK cells, regulatory T cells, follicular T helper cells, memory CD4+ T cells, and CD8+ T cells, but it is not expressed on B cells or naïve CD4+ T cells. TIGIT may be upregulated on naïve CD4+ T cells upon activation. TIGIT can interact with certain members of the PVR and PVR-like families, including CD155, and also mediates the interaction of NK and T cells with antigen presenting cells, fibroblasts, and endothelial cells that express PVR and PVR-like proteins.

MBSA43 is reported to crossreact with Rhesus macaque.
Description & Specifications

Specifications

tigit
Murine
Flow Cytometry,Functional Assay
Unlabeled
Store at 2-8°C.
Monoclonal
1mg/mL
MBSA43
VSTM3, WUCAM
RUO
Purified
Primary
aqueous buffer, no sodium azide