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Thermo Scientific™ Lab Vision™ Thymidylate Synthase Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results Thermo Scientific™ Thymidylate Synthase Ab-1, Mouse Monoclonal Antibody.

$261.12 - $1,222.63

Specifications

Antigen Thymidylate Synthase Ab-1
Clone TS 106
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunoprecipitation
View More Specs
Products
Catalog Number Mfr. No. Concentration Quantity Price Quantity    

MS471P

 
thermo scientific
MS-471-P
200�g/mL 1mL Each for $1,137.73

MS471P0

 
thermo scientific™ lab vision™
MS-471-P0
200�g/mL 100µL Each for $261.12

MS471P1

 
thermo scientific™ lab vision™
MS-471-P1
200�g/mL 500µL Each for $726.47

MS471P1ABX

 
thermo scientific™ lab vision™
MS471P1ABX
1mg/mL 100µL Each for $803.76

MS471PABX

 
thermo scientific™ lab vision™
MS-471-PABX
1mg/mL 200µL Each for $1,222.63
Description & Specifications

Specifications

Antigen Thymidylate Synthase Ab-1
Clone TS 106
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunoprecipitation
Applications Western Blotting
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunoprecipitation
Applications Western Blotting
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunoprecipitation
Applications Western Blotting
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Regulatory Status RUO
Research Discipline DNA Repair
Type Primary
Immunogen Recombinant human TS enzyme
Isotype IgG2a kappa

Provide accurate, reproducible results Thermo Scientific™ Thymidylate Synthase Ab-1, Mouse Monoclonal Antibody.

Thymidylate Synthase (TS) (EC 2.1.1.45) converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

Host Species: Mouse

Clone: TS 106

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human TS enzyme

Molecular Weight: 36kDa

Positive Control: 5-FU-resistant cell cancer lines or colon CA

Cellular Localization: Nuclear and cytoplasmic

Recommended for:

  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native verified)
  • ELISA
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO