Thermo Scientific™ Lab Vision™ Thymidine Phosphorylase/PD-ECGF Ab-1, Mouse Monoclonal Antibody
Provide accurate, reproducible results with the Thermo Scientific™ Thymidine Phosphorylase/PD-ECGF Ab-1, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS499P1ABX
Provide accurate, reproducible results with the Thermo Scientific™ Thymidine Phosphorylase/PD-ECGF Ab-1, Mouse Monoclonal Antibody.Platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
Host Species: Mouse
Species Reactivity: Human, Mouse and Rat. Others not known.
Epitope: Not determined
Immunogen: Recombinant full-length human thymidine phosphorylase (TP/PD-ECGF) protein
Molecular Weight: 55kDa (reduced)
Positive Control: HUVEC cells, Breast CA
Cellular Localization: Cytoplasmic and nuclear
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting (Not verified)
- Neutralizes Enzymatic Activity of TP/PD-ECGF (Not verified)
USA: RUO; Int'l: RUO
|Thymidine Phosphorylase/PD-ECGF Ab-1|
|Ab without BSA/Azide (Frozen)|
|Recombinant full length human thymidine phosphorylase (TP/PD-ECGF) protein|