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Thermo Scientific™ Lab Vision™ Thymidine Phosphorylase/PD-ECGF Ab-1, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ Thymidine Phosphorylase/PD-ECGF Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS499P1ABX

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Catalog No. MS499P1ABX

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Description & Specifications

Specifications

Antigen Thymidine Phosphorylase/PD-ECGF Ab-1
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone P-GF.44C
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Mouse
Immunogen Recombinant full length human thymidine phosphorylase (TP/PD-ECGF) protein
Isotype IgG1
Quantity 100µL
Regulatory Status RUO
Research Discipline Angiogenesis
Type Primary

Provide accurate, reproducible results with the Thermo Scientific™ Thymidine Phosphorylase/PD-ECGF Ab-1, Mouse Monoclonal Antibody.

Platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.

Host Species: Mouse

Clone: P-GF.44C

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: Not determined

Immunogen: Recombinant full-length human thymidine phosphorylase (TP/PD-ECGF) protein

Molecular Weight: 55kDa (reduced)

Positive Control: HUVEC cells, Breast CA

Cellular Localization: Cytoplasmic and nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not verified)
  • Neutralizes Enzymatic Activity of TP/PD-ECGF (Not verified)

Note:

USA: RUO; Int'l: RUO