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Thermo Scientific™ Lab Vision™ Thymidine Phosphorylase/PD-ECGF Ab-1, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ Thymidine Phosphorylase/PD-ECGF Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS499P1ABX

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Catalog No. MS499P1ABX

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Description & Specifications

Specifications

Antigen Thymidine Phosphorylase/PD-ECGF Ab-1
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone P-GF.44C
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Murine
Immunogen Recombinant full length human thymidine phosphorylase (TP/PD-ECGF) protein
Isotype IgG1
Quantity 100μL
Regulatory Status RUO
Research Discipline Angiogenesis
Type Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human
Target Species Murine
Target Species Rat

Provide accurate, reproducible results with the Thermo Scientific™ Thymidine Phosphorylase/PD-ECGF Ab-1, Mouse Monoclonal Antibody.

Platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.

Host Species: Mouse

Clone: P-GF.44C

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: Not determined

Immunogen: Recombinant full-length human thymidine phosphorylase (TP/PD-ECGF) protein

Molecular Weight: 55kDa (reduced)

Positive Control: HUVEC cells, Breast CA

Cellular Localization: Cytoplasmic and nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not verified)
  • Neutralizes Enzymatic Activity of TP/PD-ECGF (Not verified)

Note:

USA: RUO; Int'l: RUO