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Thermo Scientific™ Lab Vision™ Thrombospondin (TSP) Ab-3, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Thrombospondin (TSP) Ab-3, Mouse Monoclonal Antibody.

$262.47 - $1,324.76

Specifications

Antigen Thrombospondin (TSP) Ab-3
Clone C6.7
Applications Flow Cytometry,Immunofluorescence,Immunoprecipitation,Western Blotting,Flow Cytometry,Immunofluorescence,Immunoprecipitation,Western Blotting,Flow Cytometry,Immunofluorescence,Immunoprecipitation,Western Blotting,Flow Cytometry,Immunofluorescence,Immunoprecipitation,Western Blotting
Classification Monoclonal
Conjugate Unlabeled
View More Specs


Products ${productFamilyLength}
Catalog Number Mfr. No. Concentration Quantity Price Quantity  
Catalog Number Mfr. No. Concentration Quantity Price Quantity  
MS420P Thermo Scientific™ Lab Vision™
MS420P
200μg/mL 1mL Each for $1,231.61
MS420P0 Thermo Scientific™ Lab Vision™
MS420P0
200μg/mL 100μL Each for $262.47
MS420P1 Thermo Scientific™ Lab Vision™
MS420P1
200μg/mL 500μL Each for $735.53
MS420P1ABX Thermo Scientific™ Lab Vision™
MS420P1ABX
1mg/mL 100μL Each for $813.73
MS420PABX Thermo Scientific™ Lab Vision™
MS420PABX
1mg/mL 200μL Each for $1,324.76
Specifications

Description

Provide accurate, reproducible results with the Thermo Scientific™ Thrombospondin (TSP) Ab-3, Mouse Monoclonal Antibody.

Thrombospondin is a protein from platelet a-granules. It is made up of three identical subunits bound by interchain disulfides. It is secreted at sites of platelet activation and aggregation and is involved in the processes of chemotaxis, adhesion, proliferation and differentiation of leukocytes, fibroblasts, smooth muscle and endothelial cells.

Host Species: Mouse

Clone: C6.7

Isotype: IgG1

Species Reactivity: Human, Cow, Pig, Horse, Dog, Sheep and Rat. Others not known.

Epitope: Platelet- or cell-binding domain at the extreme C-terminus of TSP

Immunogen: Ca2+-replete, native purified human TSP from supernatant of thrombin-activated platelets

Molecular Weight: ∽450kDa (Nonreduced)

Cellular Localization: Secretory granules, Golgi complex, endoplasmic reticulum, extracellular matrix Ab-3 shows no cross-reaction with fibronectin, fibrinogen, and von Willebrand factor. It blocks TSP-mediated agglutination of fixed RBCs. It shows no effect on TSP-mediated agglutination of fixed, activated platelets. It inhibits both thrombin- and A23187-induced aggregation of washed, live (not fixed) platelets without affecting the secretion of serotonin. It inhibits adhesion of melanoma G361 cells to TSP. It blocks binding of C-terminal domain to Integrin-Associated Protein (IAP)/CD47.

Recommended for:

  • Immunohistochemistry (Not suitable)
  • Western Blotting (Nonreduced only)
  • Immunofluorescence
  • Immunoprecipitation (Native verified)
  • Electron Microscopy
  • Flow Cytometry
  • Blocks Binding of TSP-1 to IAP/CD47

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

Thrombospondin (TSP) Ab-3
Flow Cytometry,Immunofluorescence,Immunoprecipitation,Western Blotting,Flow Cytometry,Immunofluorescence,Immunoprecipitation,Western Blotting,Flow Cytometry,Immunofluorescence,Immunoprecipitation,Western Blotting,Flow Cytometry,Immunofluorescence,Immunoprecipitation,Western Blotting
Unlabeled
Concentrated
RUO
Primary
IgG1
C6.7
Monoclonal
Bovine,Canine,Equine,Human,Porcine,Rat,Sheep,Bovine,Canine,Equine,Human,Porcine,Rat,Sheep,Bovine,Canine,Equine,Human,Porcine,Rat,Sheep,Bovine,Canine,Equine,Human,Porcine,Rat,Sheep,Bovine,Canine,Equine,Human,Porcine,Rat,Sheep,Bovine,Canine,Equine,Human,Porcine,Rat,Sheep,Bovine,Canine,Equine,Human,Porcine,Rat,Sheep
Murine
Angiogenesis
Ca2plus-replete, native purified human TSP from supernatant of thrombin-activated platelets