Provide accurate, reproducible results with the Thermo Scientific™ Thrombospondin-1 (TSP-1) Ab-2, Mouse Monoclonal Antibody.Thrombospondin is a protein from platelet a-granules. It is made up of three identical subunits bound by interchain disulfides. It is secreted at sites of platelet activation and aggregation and is involved in the processes of chemotaxis, adhesion, proliferation and differentiation of leukocytes, fibroblasts, smooth muscle and endothelial cells.
Host Species: Mouse
Species Reactivity: Human, Mouse, Rat, Cow, Pig, Horse, Dog and Sheep. Others not known.
Epitope: Calcium-binding domain of TSP (C-terminal 50kDa piece of the 120kDa fragment)
Immunogen: Reduced and alkylated purified human TSP (fully denatured) from the supernatant of thrombin-activated platelets
Molecular Weight: ∽450kDa (nonreduced), 170 to 180kDa (reduced)
Cellular Localization: Secretory granules, Golgi complex, endoplasmic reticulum, extracellular matrix
- Immunohistochemistry (Not suitable)
- Western Blotting
- Immunoprecipitation (Native verified)
- Electron Microscopy
USA: RUO; Int'l: RUO
|Thrombospondin-1 (TSP-1) Ab-2|
|Immunoprecipitation, Western Blot|
|Reduced and alkylated purified human TSP (fully denatured) from the supernatant of thrombin-activated platelets|