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RecQ DNA Helicase Recombinant Protein, Invitrogen™


RecQ DNA Helicase Recombinant Protein, RP-4902, from Invitrogen™

Manufacturer: pierce biotechnology inc  RP4902

Catalog No. ARC4902

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Description & Specifications

Specifications

Concentration 0.5mg/mL
Conjugate Unlabeled
For Use With (Application) Control, Western Blot
Format Purified
Formulation 20μg purified protein (0.5mg/mL) in TBS with 0.05M KCl, 50% glycerol, 1mM DTT, 1mM EDTA and no preservative; pH 7.5
Molecular Weight ∽64
Name RecQ DNA Helicase Recombinant Protein
pH Range 7.5
Purification Method Chromatography
Quantity 20μg
Recombinant Yes
Source E. coli
Storage Requirements Store at -80°C, Avoid Freeze/Thaw Cycles

RecQ DNA Helicase Recombinant Protein, RP-4902, from Invitrogen.

E. coli RecQ helicase contributes to the genomic stability as the prototype of RecQ family DNA helicases, mutations of which genes are associated with premature aging and cancer susceptibility, known as Bloom’s and Werner’s syndromes. RecQ helicase functions in both early and late stages of homologous recombination and unwinds DNA with particular structures, such as the fork structure for replication, the Holliday junction which is an intermediate of recombination, telomere, quadruplex G4-DNA, etc. In replication fork, it forms a complex with topoisomerase III and regulates DNA topology.
Host Species: E. Coli
Formulation: 20μg purified protein (0.5mg/mL) in TBS with 0.05M KCl, 50% glycerol, 1mM DTT, 1mM EDTA and no preservative; pH 7.5
RP-4902 can be used as a positive control as well as in studies on mechanisms of DNA recombination, replication and repair. RP-4902 calculated molecular weight is ∽64 kDa. Purity is greater than 90%.