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HIV1 nef Recombinant Protein, Invitrogen™


HIV1 nef Recombinant Protein, RP-4922, from Invitrogen™

Manufacturer: pierce biotechnology inc  RP4922

Catalog No. ARC4922

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Description & Specifications

Specifications

Concentration 0.48mg/mL
Conjugate Unlabeled
For Use With (Application) Control, ELISA, Western Blot
Format Purified
Formulation 20μg purified protein (0.48mg/mL) in TBS with 50% glycerol, 0.01M beta mercaptoethanol and no preservative; pH 7.5
Molecular Weight ∽27
Name HIV1 nef Recombinant Protein
pH Range 7.5
Purification Method Chromatography
Quantity 20μg
Recombinant Yes
Source E. coli
Storage Requirements store at -20°C, Avoid Freeze/Thaw Cycles

HIV1 nef Recombinant Protein, RP-4922, from Invitrogen.

HIV-1 Nef is one of the accessory proteins synthesized in the early stage of AIDS virus reproduction and is abundantly found in infected cells. The name derives from its negative factor thought at the beginning but presently it is remarked as the protein which bears a most distinctive biological characteristic of AIDS virus. The protein interacts directly with the signal transduction protein of the host T cell and works effectively on AIDS infection or on long term survival of the infected cells or induces apoptosis of non-infected cells. It is also involved in the endocytosis and degradation of receptor protein of the cell surface such as CD4 and MH4, important for AIDS virus infection.
Host Species: E. Coli
Formulation: 20μg purified protein (0.48mg/mL) in TBS with 50% glycerol, 0.01M beta mercaptoethanol and no preservative; pH 7.5
RP-4922 can be used as a positive control in Western blotting with ABR antibody anti-HIV-1 Nef (PA1-4961, PA1-4962, or PA1-4963), as well as a HIV-1Nef antigen in detection of anti-HIV-1 Nef antibody in Western blotting or ELISA. RP-4922 has a calculated molecular weight of ∽27 kDa. Purity is 90%.