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Invitrogen™ Human TGF-beta 1 Recombinant Protein 
Recombinant Human Transforming Growth Factor β 1 (TGFB1) is a bioactive protein intended for use in cell culture applications. TGFB1 is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types.
Supplier: Invitrogen™ PHG9214
Description
Human TGF-beta 1 Recombinant Protein for Western Blot, IHC, ELISA, Ctrl, FN
TGFB1 acts synergistically with TGF-α in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB1 activation and signaling may result in apoptosis.
- High purity—no interference from other proteins or contaminants
- High biological activity—more results with less protein
- Proven compatibility—Gibco™ proteins bioassayed with Gibco™ media
High Purity Recombinant Bioactive Protein
Recombinant Human Transforming Growth Factor β 1 is one of more than 250 Gibco™ recombinant proteins. To help ensure Gibco™ growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.
High Biological Activity
In-house activity testing of Gibco™ Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Transforming Growth Factor β 1 (TGFB1) specific activity is determined by measuring the TGFB1 dose-dependent inhibition of proliferation of mouse HT-2 cells stimulated with mouse IL-4.
Proven Compatibility
Gibco™ proteins are bioassayed with Gibco™ media. Since 1962, Gibco™ has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.
Specifications
| Cell Culture | |
| Sequential Chromatography | |
| TGF-β1 | |
| ED50 = ≤ 0.2 ng⁄mL | |
| Store this lyophilized preparation at 2-8°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤–20°C. Avoid repeated freeze⁄thaw cycles. | |
| 10 μg | |
| Mammalian | |
| Recombinant, Ligand | |
| TGFs (Transforming Growth Factors) | |
| Gibco™ |
| 25 kDa | |
| 10μg | |
| 112 aa (2 identical) | |
| Human | |
| < 0.1 ng/μg | |
| Wet Ice | |
| Growth Factors & Receptors | |
| Lyophilized | |
| Immunology, Neurobiology, Oncology, Stem Cell Research, Cardiovascular Research, Differentiation, Bone Research |