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Alfa Aesar™ Tetraethyl methylenediphosphonate, 98+%
Manufacturer: Alfa Aesar™ A1453222
Description
ApplicationsTetraethyl methylidenediphosphonate is used in the synthesis of tetrazoloquinoline-based mono- and bisphosphonate esters. It acts as an intermediate for the synthesis of bisphosphonate and bisphosphonic acid derivatives with anticancer and antischistosomal activity. It is also used as a reactant for synthesis of dual substrate-site inhibitors of 3-deoxy-D-arabino-heputosonate 7-phosphate synthase and alpha-amino acid derivatives containing gem-biophosphonates, Lycopene through Wittig-Horner reaction. It is also used as a precursor for the preparation of dendritic polyglycerol anions.
Solubility
Slightly miscible with water.
Notes
Incompatible with strong oxidizing agents.
Specifications
| Tetraethyl methylenediphosphonate | |
| 151°C to 153°C (1.2mmHg) | |
| 1660-94-2 | |
| MFCD00039887 | |
| tetraethyl methylenediphosphonate, tetraethyl methanediphosphonate, tetraethyl diphosphonomethane, methylenebis diethylphosphonate, tetraethyl methylenebisphosphonate, phosphonic acid, methylenebis-, tetraethyl ester, methylenebis diethoxyphosphine oxide, methylenebisphosphonic acid, tetraethyl ester, phosphonic acid, methylenedi-, tetraethyl ester, methylenedi phosphonic acid tetraethyl ester | |
| CCOP(=O)(CP(=O)(OCC)OCC)OCC | |
| 288.217 | |
| 288.22 |
| >110°C (230°F) | |
| 100g | |
| C9H22O6P2 | |
| 1813241 | |
| STJWVOQLJPNAQL-UHFFFAOYSA-N | |
| 1-[diethoxyphosphorylmethyl(ethoxy)phosphoryl]oxyethane | |
| 15455 | |
| ≥98% |
Chemical Identifiers
| 1660-94-2 | |
| 288.217 | |
| STJWVOQLJPNAQL-UHFFFAOYSA-N | |
| 15455 | |
| CCOP(=O)(CP(=O)(OCC)OCC)OCC |
| C9H22O6P2 | |
| MFCD00039887 | |
| tetraethyl methylenediphosphonate, tetraethyl methanediphosphonate, tetraethyl diphosphonomethane, methylenebis diethylphosphonate, tetraethyl methylenebisphosphonate, phosphonic acid, methylenebis-, tetraethyl ester, methylenebis diethoxyphosphine oxide, methylenebisphosphonic acid, tetraethyl ester, phosphonic acid, methylenedi-, tetraethyl ester, methylenedi phosphonic acid tetraethyl ester | |
| 1-[diethoxyphosphorylmethyl(ethoxy)phosphoryl]oxyethane |
Safety and Handling
GHS H Statement
H315-H319
Causes skin irritation.
Causes serious eye irritation.
GHS P Statement
P280g-P305+P351+P338
Wear protective gloves.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Warning
RTECSNumber : SZ9150000
TSCA : TSCA