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Alfa Aesar™ Tetraethyl methylenediphosphonate, 98+%

Manufacturer:  Alfa Aesar™ A1453214

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Catalog No. AAA1453214



Description

Description

Applications
Tetraethyl methylidenediphosphonate is used in the synthesis of tetrazoloquinoline-based mono- and bisphosphonate esters. It acts as an intermediate for the synthesis of bisphosphonate and bisphosphonic acid derivatives with anticancer and antischistosomal activity. It is also used as a reactant for synthesis of dual substrate-site inhibitors of 3-deoxy-D-arabino-heputosonate 7-phosphate synthase and alpha-amino acid derivatives containing gem-biophosphonates, Lycopene through Wittig-Horner reaction. It is also used as a precursor for the preparation of dendritic polyglycerol anions.

Solubility
Slightly miscible with water.

Notes
Incompatible with strong oxidizing agents.
Specifications

Specifications

Tetraethyl methylenediphosphonate
151°C to 153°C (1.2mmHg)
1660-94-2
MFCD00039887
tetraethyl methylenediphosphonate, tetraethyl methanediphosphonate, tetraethyl diphosphonomethane, methylenebis diethylphosphonate, tetraethyl methylenebisphosphonate, phosphonic acid, methylenebis-, tetraethyl ester, methylenebis diethoxyphosphine oxide, methylenebisphosphonic acid, tetraethyl ester, phosphonic acid, methylenedi-, tetraethyl ester, methylenedi phosphonic acid tetraethyl ester
CCOP(=O)(CP(=O)(OCC)OCC)OCC
288.217
288.22
>110°C (230°F)
25g
C9H22O6P2
1813241
STJWVOQLJPNAQL-UHFFFAOYSA-N
1-[diethoxyphosphorylmethyl(ethoxy)phosphoryl]oxyethane
15455
≥98%

Chemical Identifiers

1660-94-2
288.217
STJWVOQLJPNAQL-UHFFFAOYSA-N
15455
CCOP(=O)(CP(=O)(OCC)OCC)OCC
C9H22O6P2
MFCD00039887
tetraethyl methylenediphosphonate, tetraethyl methanediphosphonate, tetraethyl diphosphonomethane, methylenebis diethylphosphonate, tetraethyl methylenebisphosphonate, phosphonic acid, methylenebis-, tetraethyl ester, methylenebis diethoxyphosphine oxide, methylenebisphosphonic acid, tetraethyl ester, phosphonic acid, methylenedi-, tetraethyl ester, methylenedi phosphonic acid tetraethyl ester
1-[diethoxyphosphorylmethyl(ethoxy)phosphoryl]oxyethane
Safety and Handling

Safety and Handling

GHS H Statement
H315-H319
Causes skin irritation.
Causes serious eye irritation.

GHS P Statement
P280g-P305+P351+P338
Wear protective gloves.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Warning

RTECSNumber : SZ9150000

TSCA : TSCA

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